SLC9A1 and SLC45A1

Data Source:
BioGRID (two hybrid)

		SLC9A1	SLC45A1
Description		solute carrier family 9 member A1	solute carrier family 45 member 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Cell Surface Intercalated Disc Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane Lamellipodium T-tubule Membrane Raft Perinuclear Region Of Cytoplasm Extracellular Exosome Cation-transporting ATPase Complex	Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Calmodulin Binding Phosphatidylinositol-4,5-bisphosphate Binding Solute:proton Antiporter Activity Sodium:proton Antiporter Activity Potassium:proton Antiporter Activity Protein Phosphatase 2B Binding Protein-macromolecule Adaptor Activity Calcium-dependent Protein Binding Molecular Adaptor Activity Sodium:proton Antiporter Activity Involved In Regulation Of Cardiac Muscle Cell Membrane Potential	Sucrose:proton Symporter Activity
	Biological Process	Ion Transport Cellular Sodium Ion Homeostasis Regulation Of PH Response To Acidic PH Positive Regulation Of Cardiac Muscle Hypertrophy Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Cell Migration Maintenance Of Cell Polarity Hyaluronan Catabolic Process Positive Regulation Of Cell Growth Cellular Response To Insulin Stimulus Positive Regulation Of Mitochondrial Membrane Permeability Response To Muscle Stretch Sodium Ion Export Across Plasma Membrane Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Action Potential Positive Regulation Of Transcription By RNA Polymerase II Protein Complex Oligomerization Regulation Of Intracellular PH Regulation Of Stress Fiber Assembly Regulation Of Focal Adhesion Assembly Regulation Of Sensory Perception Of Pain Cardiac Muscle Cell Differentiation Cellular Response To Cold Positive Regulation Of Calcineurin-NFAT Signaling Cascade Neuron Death Cellular Response To Antibiotic Cellular Response To Electrical Stimulus Cellular Response To Mechanical Stimulus Cellular Response To Hypoxia Cellular Response To Acidic PH Potassium Ion Transmembrane Transport Cellular Response To Epinephrine Stimulus Cardiac Muscle Cell Contraction Regulation Of Cardiac Muscle Cell Membrane Potential Regulation Of The Force Of Heart Contraction By Cardiac Conduction Anion Transmembrane Transport Sodium Ion Import Across Plasma Membrane Positive Regulation Of The Force Of Heart Contraction Proton Transmembrane Transport Positive Regulation Of Calcium:sodium Antiporter Activity	Sucrose Transport Glucose Transmembrane Transport
Pathways		Hyaluronan uptake and degradation Sodium/Proton exchangers
Drugs		Amiloride Homoserine Lactone Cariporide
Diseases
GWAS		Lateral ventricle volume ( 31530798)	Allergic rhinitis ( 30013184) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Blond vs. brown/black hair color ( 30531825) Breast cancer ( 23468962) Brown vs. black hair color ( 30531825) Depression ( 29700475) Fish- and plant-related diet ( 32066663) Hair color ( 29662168) Hair shape ( 29220522) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Hippocampal volume in normal cognition ( 29274321) Inflammatory skin disease ( 25574825) Morning person ( 30696823) Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) ( 24823311) Psoriasis ( 25903422 23143594) Schizophrenia ( 28991256 29483656) Strep throat ( 28928442) Subclinical trait of interstitial lung disease (basilar peel-core ratio of high attentuation areas on CT scan) ( 28521775) Youthful appearance (self-reported) ( 32339537)
Interacting Genes		12 interacting genes: CA2 CHP1 CHP2 DAXX MAP3K14 MAP4K4 MAPK1 MAPK14 MDFI TESC WNK1 YWHAB	1 interacting genes: PPP1CA
Entrez ID		6548	50651
HPRD ID		00123	19078
Ensembl ID		ENSG00000090020	ENSG00000162426
Uniprot IDs		B2RAH2 P19634	Q9Y2W3
PDB IDs		1Y4E 2BEC 2E30 2HTG 2KBV 2L0E 2MDF 2YGG 6BJF 6NUC 6NUF 6NUU
Enriched GO Terms of Interacting Partners?
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