SLC8A2 and GPR37

Data Source:
BioGRID (two hybrid)

		SLC8A2	GPR37
Description		solute carrier family 8 member A2	G protein-coupled receptor 37
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Postsynaptic Density Membrane Basolateral Plasma Membrane Axon Dendrite Sarcolemma Neuronal Cell Body Dendritic Spine Perikaryon Axon Terminus Synapse Presynapse Postsynapse	Ubiquitin Ligase Complex Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Receptor Complex
	Molecular Function	Calcium:sodium Antiporter Activity Calmodulin Binding Sodium Ion Transmembrane Transporter Activity Calcium Ion Transmembrane Transporter Activity Cation:cation Antiporter Activity Metal Ion Binding Calcium:cation Antiporter Activity Involved In Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration	G Protein-coupled Receptor Activity Protein Binding Neuropeptide Receptor Activity G Protein-coupled Peptide Receptor Activity Hsp70 Protein Binding Heat Shock Protein Binding Ubiquitin Protein Ligase Binding Prosaposin Receptor Activity Peptide Binding Neuropeptide Binding
	Biological Process	Response To Ischemia Ion Transport Cellular Calcium Ion Homeostasis Cell Communication Learning Or Memory Learning Memory Regulation Of Gene Expression Metal Ion Transport Sodium Ion Transmembrane Transport Regulation Of Short-term Neuronal Synaptic Plasticity Synapse Organization Cognition Regulation Of Cytosolic Calcium Ion Concentration Long-term Synaptic Potentiation Neuron Cellular Homeostasis Calcium Ion Transmembrane Transport Positive Regulation Of Protein Serine/threonine Kinase Activity Calcium Ion Import Across Plasma Membrane Modulation Of Excitatory Postsynaptic Potential Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration Regulation Of Action Potential Firing Pattern Regulation Of Calcineurin-mediated Signaling Transport Across Blood-brain Barrier Regulation Of Cardiac Conduction Calcium Ion Export Across Plasma Membrane	G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Locomotion Involved In Locomotory Behavior Dopamine Biosynthetic Process Positive Regulation Of MAPK Cascade Positive Regulation Of Dopamine Metabolic Process Negative Regulation Of Hydrogen Peroxide-induced Cell Death
Pathways		Reduction of cytosolic Ca++ levels Sodium/Calcium exchangers Ion homeostasis	Peptide ligand-binding receptors G alpha (i) signalling events
Drugs
Diseases
GWAS		Resting-state electroencephalogram vigilance ( 29703947)	Ankylosing spondylitis ( 23749187) Cutaneous malignant melanoma ( 32341527 26237428) Nevus count or cutaneous melanoma ( 32341527) Reading and spelling ( 23738518) Refractive error ( 32231278)
Interacting Genes		7 interacting genes: GPR35 GPR37 PPP3CB YWHAB YWHAE YWHAQ YWHAZ	51 interacting genes: ADGRB1 ADORA2A ADRA1A ADRB2 BNIP3 CCNQ CNTN1 DRD2 ERGIC3 FA2H FKBP8 FUCA2 G6PC3 GABARAPL2 GABBR1 GHITM GLP1R GPR17 GRIP1 HDGF HLA-C HSP90B1 HSPA1A HTR2C HTR4 IFITM3 JKAMP LTB4R2 P4HTM PPM1J PRKN SDCBP SLC37A1 SLC3A2 SLC41A3 SLC8A2 SPATA2L STUB1 SYVN1 TAFA5 TMED1 TMEM161A TMEM175 TMEM231 TMEM63A TTYH1 TTYH2 WLS YIF1A YIF1B ZDHHC11
Entrez ID		6543	2861
HPRD ID		15990	03992
Ensembl ID		ENSG00000118160	ENSG00000170775
Uniprot IDs		Q9UPR5	O15354
PDB IDs
Enriched GO Terms of Interacting Partners?
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