SLC6A8 and TAZ

Data Source:
BioGRID (affinity chromatography technology)

		SLC6A8	TAZ
Description		solute carrier family 6 member 8	tafazzin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane	Mitochondrion Mitochondrial Inner Membrane Integral Component Of Membrane Mitochondrial Membrane
	Molecular Function	Molecular_function Creatine Transmembrane Transporter Activity Creatine:sodium Symporter Activity	1-acylglycerol-3-phosphate O-acyltransferase Activity O-acyltransferase Activity 1-acylglycerophosphocholine O-acyltransferase Activity
	Biological Process	Creatine Metabolic Process Neurotransmitter Transport Muscle Contraction Creatine Transmembrane Transport Sodium Ion Transmembrane Transport Nitrogen Compound Transport	Muscle Contraction Inner Mitochondrial Membrane Organization Heart Development Skeletal Muscle Tissue Development Hemopoiesis Cardiolipin Biosynthetic Process Mitochondrial Respiratory Chain Complex I Assembly Cardiolipin Acyl-chain Remodeling Cristae Formation Mitochondrial ATP Synthesis Coupled Electron Transport Cardiac Muscle Tissue Development Cardiac Muscle Contraction
Pathways		Creatine metabolism	Mitochondrial protein import Mitochondrial protein import Acyl chain remodeling of CL
Drugs		Creatine Phosphocreatine
Diseases		Syndromic X-linked mental retardation with epilepsy or seizures, including: West syndrome (WS); Partington syndrome (PRTS); Proud syndrome (ACCAG); XMR and epilepsy (XMRE); MRXHF1; XMR OPHN1-related (MRXSO) ; XELBD; XMR, Christianson type (MRXSC); Creatine deficiency syndrome (XL-CDS); Renpenning syndrome (RENS1); Epilepsy and mental retardation limited to females (EFMR); Periventricular nodular heterotopia (PVNH); Hydrocephalus (XLH); XMR, JARID1C related (MRXSJ); Boerjeson-Forssman syndrome (BFLS); CK syndrome (CKS) Non-syndromic X-linked mental retardation Creatine deficiency syndrome, including: Arginine:glycine amidinotransferase deficiency (AGAT deficiency); Guanidinoacetate methyltransferase deficiency (GAMT deficiency); X-linked creatine deficiency syndrome (XL-CDS)	3-Methylglutaconic aciduria (MGCA) Barth syndrome (BTHS) Dilated cardiomyopathy (DCM)
GWAS
Interacting Genes		3 interacting genes: BDKRB1 CD59 CHRM5	9 interacting genes: BTRC CHGB CSNK1E GSK3B LATS1 LATS2 RUNX1 SLC9A3R2 YWHAE
Entrez ID		6535	6901
HPRD ID		02073	02316
Ensembl ID		ENSG00000130821	ENSG00000102125
Uniprot IDs		P48029 Q59EV7 X5D9C4	A0A0S2Z4E6 A0A0S2Z4F4 A0A0S2Z4K0 A0A0S2Z4K9 A0A494C0C5 A0A499FJ53 A6XNE1 Q16635
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?