C8orf33 and KCTD6

Data Source:
BioGRID (two hybrid)

		C8orf33	KCTD6
Description		chromosome 8 open reading frame 33	potassium channel tetramerization domain containing 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytosol M Band
	Molecular Function	Protein Binding	Protein Binding Ankyrin Binding Identical Protein Binding Cullin Family Protein Binding
	Biological Process		Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Regulation Of Intracellular Estrogen Receptor Signaling Pathway Regulation Of Growth Post-translational Protein Modification Negative Regulation Of Smoothened Signaling Pathway Protein Homooligomerization
Pathways			RUNX1 regulates estrogen receptor mediated transcription Neddylation Estrogen-dependent gene expression Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Hepcidin/transferrin saturation ratio ( 27846281) Refractive error ( 32231278) Systemic lupus erythematosus ( 28714469) vWF levels ( 30586737)
Interacting Genes		49 interacting genes: AAMP ALAS1 APP BLOC1S2 BRD4 CEP70 CRELD2 DISC1 DVL3 EDRF1 EPS8 FAM9B FEZ1 FST FYN GIT1 GPRASP1 HAP1 HMBOX1 IKZF1 IMMT KBTBD7 KCTD6 KRTAP10-7 LZTS2 MAPK8IP2 MCC MDFI MRFAP1 NACC1 NGEF NOL7 PI4KA PICK1 PNMA1 RASSF1 SF3B2 TAOK1 TNIP1 TRIM23 TRIM41 TUBA1A TUBB2B WIZ ZC3H15 ZFP28 ZNF205 ZNF331 ZNF526	28 interacting genes: ACTN1 ACTN3 ANK1 BAG4 C8orf33 CDC23 CTNND1 CUL3 EHHADH ERBB2 FAM124B GOLGA8EP GOLGA8F GRB7 GSDMD LNX1 MOS NTAQ1 PICK1 PPIG PRPF31 PSMA1 REL SDCBP TBC1D2 TCEANC TEPSIN ZCCHC10
Entrez ID		65265	200845
HPRD ID		07951	13769
Ensembl ID		ENSG00000182307	ENSG00000168301
Uniprot IDs		Q9H7E9	Q8NC69
PDB IDs
Enriched GO Terms of Interacting Partners?
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