SLC1A4 and ERVW-1

Data Source:
HPRD (in vitro, in vivo)

		SLC1A4	ERVW-1
Description		solute carrier family 1 member 4	endogenous retrovirus group W member 1, envelope
Image		No pdb structure
GO Annotations	Cellular Component	Centrosome Intermediate Filament Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Dendrite Melanosome Neuronal Cell Body Synapse Extracellular Exosome	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Chloride Channel Activity Amino Acid Transmembrane Transporter Activity L-alanine Transmembrane Transporter Activity L-aspartate Transmembrane Transporter Activity L-cystine Transmembrane Transporter Activity L-glutamine Transmembrane Transporter Activity L-proline Transmembrane Transporter Activity L-serine Transmembrane Transporter Activity L-threonine Transmembrane Transporter Activity Symporter Activity L-hydroxyproline Transmembrane Transporter Activity
	Biological Process	Amino Acid Transport Glutamine Transport L-alanine Transport L-cystine Transport Proline Transport L-serine Transport Threonine Transport Hydroxyproline Transport Synaptic Transmission, Glutamatergic Proline Transmembrane Transport Cognition L-aspartate Import Across Plasma Membrane Transport Across Blood-brain Barrier Chloride Transmembrane Transport L-serine Import Across Plasma Membrane L-alanine Import Across Plasma Membrane	Syncytium Formation By Plasma Membrane Fusion Syncytium Formation Myoblast Fusion Anatomical Structure Morphogenesis
Pathways		Amino acid transport across the plasma membrane
Drugs		Alanine
Diseases
GWAS		Atrial fibrillation ( 28416822) Blood metabolite levels ( 24816252) Ejection fraction ( 29403010) Fractional shortening ( 29403010) Left ventricular internal dimension in systole ( 29403010) Metabolite levels ( 22286219 22916037) Metabolite levels (small molecules and protein measures) ( 27005778) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes		2 interacting genes: ERVW-1 F2RL1	2 interacting genes: SLC1A4 SLC1A5
Entrez ID		6509	30816
HPRD ID		02576	05231
Ensembl ID		ENSG00000115902	ENSG00000242950
Uniprot IDs		P43007	D0EYG5 Q9UQF0
PDB IDs			5HA6 6RX1
Enriched GO Terms of Interacting Partners?
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