SLC4A3 and CA4

Data Source:
HPRD (in vivo, in vitro)

		SLC4A3	CA4
Description		solute carrier family 4 member 3	carbonic anhydrase 4
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Membrane	Rough Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Trans-Golgi Network Plasma Membrane Cell Surface Membrane Basolateral Plasma Membrane Apical Plasma Membrane Transport Vesicle Membrane Secretory Granule Membrane Anchored Component Of External Side Of Plasma Membrane Brush Border Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Inorganic Anion Exchanger Activity Protein Binding Bicarbonate Transmembrane Transporter Activity Anion:anion Antiporter Activity Transmembrane Transporter Activity	Carbonate Dehydratase Activity Protein Binding Zinc Ion Binding Hydro-lyase Activity
	Biological Process	Inorganic Anion Transport Bicarbonate Transport Ion Homeostasis Regulation Of Intracellular PH Transmembrane Transport Cardiac Conduction Cardiac Muscle Cell Action Potential Anion Transmembrane Transport Transport Across Blood-brain Barrier	One-carbon Metabolic Process Bicarbonate Transport
Pathways		Bicarbonate transporters	Erythrocytes take up carbon dioxide and release oxygen Erythrocytes take up oxygen and release carbon dioxide Reversible hydration of carbon dioxide
Drugs			Methyclothiazide Topiramate Ethoxzolamide Bendroflumethiazide Benzthiazide Benzthiazide Cyclothiazide Methazolamide Hydroflumethiazide Acetazolamide Dorzolamide Zonisamide Trichlormethiazide Diclofenamide Brinzolamide Ellagic acid Sodium carbonate
Diseases			Retinitis pigmentosa (RP)
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Immune response to measles-mumps-rubella vaccine ( 24811271) QT interval ( 29874175)
Interacting Genes		5 interacting genes: ANK1 CA2 CA4 DRD2 PRKCE	5 interacting genes: PIH1D1 PRDX2 SLC4A1 SLC4A3 SLC4A4
Entrez ID		6508	762
HPRD ID		00109	00261
Ensembl ID		ENSG00000114923	ENSG00000167434
Uniprot IDs		P48751	P22748
PDB IDs			1ZNC 3F7B 3F7U 3FW3 5IPZ 5JN8 5JN9 5JNA 5JNC 5KU6
Enriched GO Terms of Interacting Partners?
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