REEP1 and UNC93B1

Data Source:
BioGRID (two hybrid)

		REEP1	UNC93B1
Description		receptor accessory protein 1	unc-93 homolog B1, TLR signaling regulator
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytoplasmic Microtubule Membrane Integral Component Of Membrane Mitochondrial Membrane Endoplasmic Reticulum Tubular Network	Golgi Membrane Lysosome Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Early Phagosome
	Molecular Function	Protein Binding Microtubule Binding Olfactory Receptor Binding	Protein Binding Toll-like Receptor Binding
	Biological Process	Protein Insertion Into Membrane Endoplasmic Reticulum Tubular Network Organization	Toll-like Receptor Signaling Pathway Adaptive Immune Response Intracellular Protein Transport Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 7 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Innate Immune Response Defense Response To Virus
Pathways		Olfactory Signaling Pathway	Trafficking and processing of endosomal TLR UNC93B1 deficiency - HSE
Drugs
Diseases		Hereditary spastic paraplegia (SPG)
GWAS		Atrial fibrillation ( 30061737 29892015) Facial emotion recognition (sad faces) ( 28608620) Night sleep phenotypes ( 27126917)
Interacting Genes		7 interacting genes: CLDN10 CSRP1 STX7 TMEM100 TMEM42 TMEM97 UNC93B1	27 interacting genes: BEST2 CCDC107 CD79A CLDN7 CLPTM1 CREB3L1 EBP ERGIC3 FATE1 FFAR3 GPR101 GPR37L1 GPRC5D HHLA2 KLRC1 LDLRAD1 LEUTX LIME1 MBOAT7 MFF REEP1 SLC16A2 SLC35C2 SSMEM1 SYNDIG1 TM4SF18 TMEM237
Entrez ID		65055	81622
HPRD ID		07810	12191
Ensembl ID		ENSG00000068615	ENSG00000110057
Uniprot IDs		Q9H902	Q9H1C4
PDB IDs
Enriched GO Terms of Interacting Partners?
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