GINS3 and SETD6

Data Source:
BioGRID (biochemical)

		GINS3	SETD6
Description		GINS complex subunit 3	SET domain containing 6, protein lysine methyltransferase
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GO Annotations	Cellular Component	GINS Complex Nucleoplasm CMG Complex	Nucleus Nucleoplasm Cytosol
	Molecular Function	Protein Binding	Protein Binding Protein-lysine N-methyltransferase Activity NF-kappaB Binding
	Biological Process	DNA Strand Elongation Involved In DNA Replication Mitotic DNA Replication Initiation	Peptidyl-lysine Monomethylation Stem Cell Population Maintenance Negative Regulation Of NF-kappaB Transcription Factor Activity Histone Lysine Methylation Stem Cell Differentiation Regulation Of Inflammatory Response
Pathways		Unwinding of DNA Unwinding of DNA	PKMTs methylate histone lysines
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits ( 32602732) QT interval ( 19305408) TPE interval (resting) ( 32386560)	Autism spectrum disorder or schizophrenia ( 28540026) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Pulse pressure ( 30578418) QT interval ( 29213071) Schizophrenia ( 29483656)
Interacting Genes		8 interacting genes: CTNNA3 GINS4 KRT80 MEOX2 MYO15B SMARCD1 TRAPPC6A VAC14	1 interacting genes: ATXN1
Entrez ID		64785	79918
HPRD ID		07842	07956
Ensembl ID		ENSG00000181938	ENSG00000103037
Uniprot IDs		A0A0S2Z5L0 A0A0S2Z5L4 A0A0S2Z5P2 Q9BRX5	Q8TBK2
PDB IDs		2E9X 2EHO 2Q9Q 6XTX 6XTY	3QXY 3RC0
Enriched GO Terms of Interacting Partners?
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