ALDH8A1 and IFT88

Data Source:
BioGRID (genetic interference)

		ALDH8A1	IFT88
Description		aldehyde dehydrogenase 8 family member A1	intraflagellar transport 88
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Extracellular Exosome	Cytoplasm Centrosome Centriole Cilium Intraciliary Transport Particle B Motile Cilium Ciliary Basal Body Sperm Flagellum Ciliary Tip Ciliary Base Non-motile Cilium
	Molecular Function	Retinal Dehydrogenase Activity Aminomuconate-semialdehyde Dehydrogenase Activity	Protein Binding Kinesin Binding
	Biological Process	Retinoic Acid Metabolic Process Retinal Metabolic Process 9-cis-retinoic Acid Biosynthetic Process L-kynurenine Catabolic Process	Kidney Development Intraciliary Transport Involved In Cilium Assembly Intraciliary Transport Inner Ear Receptor Cell Stereocilium Organization Cilium Assembly Regulation Of Cilium Assembly Non-motile Cilium Assembly Regulation Of Autophagosome Assembly
Pathways		RA biosynthesis pathway	Hedgehog 'off' state Intraflagellar transport Intraflagellar transport Chaperone Mediated Autophagy Late endosomal microautophagy Aggrephagy Aggrephagy
Drugs
Diseases
GWAS		Coronary artery calcification ( 23870195) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Pulse pressure ( 30224653)	Coronary artery calcification ( 23870195) Dental caries ( 23064961) Schizophrenia, bipolar disorder and depression (combined) ( 20713499) Sulfasalazine-induced agranulocytosis ( 28762467)
Interacting Genes		1 interacting genes: APP	10 interacting genes: CAPN7 CCDC120 EEF2KMT EML2 FBXO7 ITPKB MSRB1 PRRC2A RPGR SMARCE1
Entrez ID		64577	8100
HPRD ID		06974	09000
Ensembl ID		ENSG00000118514	ENSG00000032742
Uniprot IDs		Q9H2A2	A0A140VJL7 B3KX42 Q13099
PDB IDs
Enriched GO Terms of Interacting Partners?
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