NKX2-4 and NOTO

Data Source:
BioGRID (two hybrid)

		NKX2-4	NOTO
Description		NK2 homeobox 4	notochord homeobox
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Cellular_component Nucleus	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Molecular_function Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Biological_process Cell Differentiation	Heart Looping Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Embryonic Pattern Specification Dorsal/ventral Pattern Formation Neuron Differentiation Notochord Development Motile Cilium Assembly Regulation Of Cilium Assembly
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Autism spectrum disorder ( 30804558) Lupus nephritis in systemic lupus erythematosus ( 24925725) Metabolite levels ( 23823483)	General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435)
Interacting Genes		1 interacting genes: NOTO	31 interacting genes: ANKRD11 APOBEC1 BAG3 BANP BTF3 CCDC120 CEP19 CHAF1A EIPR1 ETV3L FAM9B FOXD2 FOXH1 GLYCTK HNRNPK IP6K3 KRT34 KRTAP19-7 KRTAP5-6 KRTAP6-1 KRTAP6-3 LDLRAP1 LRP10 MAGED1 MEIS2 NKX2-4 PIH1D2 POU4F2 SBK3 TTC23 UBTFL1
Entrez ID		644524	344022
HPRD ID
Ensembl ID		ENSG00000125816	ENSG00000214513
Uniprot IDs		Q9H2Z4	A8MTQ0
PDB IDs
Enriched GO Terms of Interacting Partners?
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