WIPF3 and VSTM2L

Data Source:
HPRD (in vitro, in vivo)

		WIPF3	VSTM2L
Description		WAS/WASL interacting protein family member 3	V-set and transmembrane domain containing 2 like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Actin Filament	Extracellular Region Cytoplasm Plasma Membrane Axon
	Molecular Function	Actin Binding SH3 Domain Binding	Protein Binding Cell-cell Adhesion Mediator Activity
	Biological Process	Multicellular Organism Development Spermatogenesis Actin Filament-based Movement Cell Differentiation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Axon Guidance Negative Regulation Of Neuron Apoptotic Process Dendrite Self-avoidance
Pathways		Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Corneal curvature ( 22969067) Facial emotion recognition ( 28608620) Facial emotion recognition (angry faces) ( 28608620) Facial emotion recognition (sad faces) ( 28608620) Heel bone mineral density ( 30598549) Microalbuminuria ( 31511532) Urinary albumin excretion ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189 31511532)	Levodopa wearing off effect (time symptoms uncontrolled) in Parkinson's disease (response to zonisamide) ( 32355309)
Interacting Genes		2 interacting genes: VSTM2L WASL	3 interacting genes: ATXN1 SRPK2 WIPF3
Entrez ID		644150	128434
HPRD ID		18947	12735
Ensembl ID		ENSG00000122574	ENSG00000132821
Uniprot IDs		A6NGB9	Q96N03
PDB IDs
Enriched GO Terms of Interacting Partners?
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