TMEM72 and MS4A1

Data Source:
BioGRID (two hybrid)

		TMEM72	MS4A1
Description		transmembrane protein 72	membrane spanning 4-domains A1
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Extracellular Space Nucleoplasm Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface Plasma Membrane Raft Extracellular Exosome
	Molecular Function	Protein Binding	Epidermal Growth Factor Receptor Binding Protein Binding Immunoglobulin Binding MHC Class II Protein Complex Binding Identical Protein Binding
	Biological Process		Store-operated Calcium Entry Humoral Immune Response Response To Bacterium B Cell Differentiation B Cell Proliferation B Cell Activation B Cell Receptor Signaling Pathway Protein Tetramerization Calcium Ion Import Into Cytosol
Pathways
Drugs			Rituximab Ibritumomab tiuxetan Tositumomab Ofatumumab Obinutuzumab Technetium Tc-99m nofetumomab merpentan Ocrelizumab
Diseases
GWAS		Body mass index ( 25760438) Diastolic blood pressure ( 27841878) Moderate or severe prolonged lymphopenia in dimethyl fumarate-treated relapsing-remitting multiple sclerosis ( 31749835) Refractive error ( 32231278) Selective IgA deficiency ( 27723758)	Recurrent major depressive disorder ( 29317602)
Interacting Genes		10 interacting genes: BCL2L13 CERS4 FAM209A FXYD6 GJA8 LENEP MS4A1 PIGY SLC35A5 TMEM237	41 interacting genes: ACKR2 AQP6 CD40 CERS4 CLEC14A CREB3 CREB3L1 CSNK2A1 CSNK2A2 FAM209A FCRL3 FYN GORAB GPR42 HSD17B11 HSD17B13 IL7R KASH5 LCK LEUTX LMNA LYN MDM2 MFSD14B MMD MTIF3 REEP2 REEP4 RNF19B RNF5 SLC10A1 SLC10A6 SLC18A1 SLC35C2 THAP4 TMEM31 TMEM72 TMEM82 TMPPE TMX2 TSPO2
Entrez ID		643236	931
HPRD ID			00204
Ensembl ID		ENSG00000187783	ENSG00000156738
Uniprot IDs		A0PK05	A0A024R507 P11836
PDB IDs			1S8B 2OSL 3BKY 3PP4 6VJA 6Y90 6Y92 6Y97 6Y9A
Enriched GO Terms of Interacting Partners?
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