TSPYL2 and ZFP91

Data Source:
BioGRID (two hybrid)

		TSPYL2	ZFP91
Description		TSPY like 2	ZFP91 zinc finger protein, atypical E3 ubiquitin ligase
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Nucleolus Cytoplasm	Nucleus Nucleoplasm Nucleolus
	Molecular Function	RDNA Binding Chromatin Binding Protein Binding Histone Binding	Ubiquitin-protein Transferase Activity Metal Ion Binding
	Biological Process	Nucleosome Assembly Cell Cycle Negative Regulation Of DNA Replication Regulation Of Signal Transduction Negative Regulation Of Cell Growth IRE1-mediated Unfolded Protein Response Negative Regulation Of Cell Cycle Regulation Of Protein Kinase Activity	Regulation Of Transcription By RNA Polymerase II Activation Of NF-kappaB-inducing Kinase Activity Protein K63-linked Ubiquitination
Pathways		XBP1(S) activates chaperone genes
Drugs
Diseases
GWAS			Chronotype ( 30696823) HDL cholesterol levels ( 32203549) Medication use (calcium channel blockers) ( 31015401) Morning person ( 30696823) Systolic blood pressure ( 30578418) Ulcerative colitis ( 28067908)
Interacting Genes		46 interacting genes: ABT1 AEBP2 APTX CASK CCNB1 CDK1 CDK2 CDK4 CEP19 COIL CREBBP CSNK2A1 EEF1A1 GFI1B H2BC15 HMGXB4 INO80B KMT5B LMO2 LNX1 MCRS1 NOL12 NOP53 PHF19 RBM15 RNF151 RPS25 SIRT6 SNIP1 TBC1D26 TMA16 TNNT1 TSPYL1 XAGE1A XAGE1B ZBTB24 ZBTB48 ZFP1 ZFP91 ZNF280C ZNF286A ZNF329 ZNF524 ZNF687 ZNF775 ZNF835	12 interacting genes: CDKN2A CEP70 CRBN FAM9A MAP3K14 PICK1 POU6F2 SRPK2 TP53BP2 TSPYL2 ZFP41 ZNF526
Entrez ID		64061	80829
HPRD ID		06713	11700
Ensembl ID		ENSG00000184205	ENSG00000186660
Uniprot IDs		Q9H2G4	A0A024R4Z1 A0A024R4Z4 Q96JP5
PDB IDs			2M9A
Enriched GO Terms of Interacting Partners?
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