SDHB and TARBP1

Data Source:
BioGRID (protein complementation assay, affinity chromatography technology, affinity chromatography technology)
HPRD (in vitro, in vivo)

		SDHB	TARBP1
Description		succinate dehydrogenase complex iron sulfur subunit B	TAR (HIV-1) RNA binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex II, Succinate Dehydrogenase Complex (ubiquinone) Plasma Membrane Mitochondrial Membrane	Nucleus
	Molecular Function	Protein Binding Succinate Dehydrogenase (ubiquinone) Activity Electron Transfer Activity Metal Ion Binding Ubiquinone Binding 2 Iron, 2 Sulfur Cluster Binding 3 Iron, 4 Sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding	RNA Binding TRNA (guanine) Methyltransferase Activity
	Biological Process	Tricarboxylic Acid Cycle Succinate Metabolic Process Aerobic Respiration Respiratory Electron Transport Chain	Regulation Of Transcription By RNA Polymerase II TRNA Methylation
Pathways		Respiratory electron transport Citric acid cycle (TCA cycle)
Drugs		2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol Ubiquinone Q1
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Height ( 20189936) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Cognitive test performance ( 17903297) Psoriasis ( 25854761)
Interacting Genes		6 interacting genes: ABCA1 CARTPT GEM PIK3R5 SPRY2 XRN1	1 interacting genes: SREK1
Entrez ID		6390	6894
HPRD ID		01707	05445
Ensembl ID		ENSG00000117118	ENSG00000059588
Uniprot IDs		P21912	Q13395
PDB IDs			2HA8
Enriched GO Terms of Interacting Partners?
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