RNF123 and TMPO

Data Source:
BioGRID (enzymatic study)

		RNF123	TMPO
Description		ring finger protein 123	thymopoietin
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GO Annotations	Cellular Component	Cytoplasm Cytosol Nuclear Membrane	Chromatin Nucleus Nuclear Envelope
	Molecular Function	Ubiquitin-protein Transferase Activity Metal Ion Binding	DNA Binding Protein Binding Lamin Binding Cadherin Binding
	Biological Process	Protein Ubiquitination Protein Deubiquitination Proteolysis Involved In Cellular Protein Catabolic Process	Regulation Of Transcription, DNA-templated
Pathways		Ub-specific processing proteases Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Age at first birth ( 27798627) Blood protein levels ( 28240269) Body mass index ( 26426971) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Depressive symptoms (binary sum-score) ( 31530331) Extremely high intelligence ( 29520040) Hemoglobin levels ( 32327693) Household income ( 31844048) Household income (MTAG) ( 31844048) Inflammatory bowel disease ( 28067908) Morning person ( 30696823) Multisite chronic pain ( 31194737) Refractive error ( 32231278) Regular attendance at a gym or sports club ( 29970889) Regular attendance at a religious group ( 29970889) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)	Metabolite levels ( 23823483)
Interacting Genes		14 interacting genes: CDKN1B EMD LMNA LMNB1 MTDH RB1 SMAD2 SMAD9 TMPO UBAC1 UBC UBE2D1 UBE2D2 UBE2W	22 interacting genes: ABL1 AKAP8L BANF1 CLK1 CSNK2A1 GMCL1 GOLM1 HDAC3 KLHL6 LMNA LMNB1 LMNB2 OIP5 RB1 RNF123 SGTA SGTB SRC SRPK2 STOM SUMO2 USP7
Entrez ID		63891	7112
HPRD ID		11499	01777
Ensembl ID		ENSG00000164068	ENSG00000120802
Uniprot IDs		Q5XPI4	A0A024RBE7 A0A024RBH7 G5E972 P42166 P42167 Q59G12
PDB IDs		2MA6	1GJJ 1H9E 1H9F
Enriched GO Terms of Interacting Partners?
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