SRR and RNF41

Data Source:
BioGRID (two hybrid)

		SRR	RNF41
Description		serine racemase	ring finger protein 41
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Neuronal Cell Body Apical Part Of Cell	Cytosol Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Tubular Network
	Molecular Function	Magnesium Ion Binding L-serine Ammonia-lyase Activity Calcium Ion Binding Protein Binding ATP Binding D-serine Ammonia-lyase Activity Glycine Binding Threonine Racemase Activity PDZ Domain Binding Pyridoxal Phosphate Binding Serine Racemase Activity Identical Protein Binding Protein Homodimerization Activity	Ubiquitin-protein Transferase Activity Erythropoietin Receptor Binding Interleukin-3 Receptor Binding Protein Binding Zinc Ion Binding Protein Domain Specific Binding Receptor Tyrosine Kinase Binding Small GTPase Binding Identical Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	L-serine Metabolic Process L-serine Biosynthetic Process Brain Development Aging Serine Family Amino Acid Metabolic Process Response To Lipopolysaccharide Response To Drug Pyruvate Biosynthetic Process Response To Morphine D-serine Metabolic Process D-serine Biosynthetic Process	Protein Polyubiquitination Autophagy Negative Regulation Of Cell Population Proliferation Proteasomal Protein Catabolic Process Protein Ubiquitination Negative Regulation Of Cell Migration Regulation Of MAPK Cascade Regulation Of Lymphocyte Differentiation Regulation Of Myeloid Cell Differentiation Positive Regulation Of Protein Catabolic Process Positive Regulation Of DNA-binding Transcription Factor Activity Protein Autoubiquitination Regulation Of Protein Kinase B Signaling Extrinsic Apoptotic Signaling Pathway Negative Regulation Of Mitophagy Regulation Of Establishment Of Cell Polarity Regulation Of Reactive Oxygen Species Metabolic Process Positive Regulation Of Reactive Oxygen Species Metabolic Process
Pathways		Serine biosynthesis	Downregulation of ERBB2:ERBB3 signaling Antigen processing: Ubiquitination & Proteasome degradation
Drugs		Pyridoxal phosphate Serine
Diseases
GWAS		Aortic root size ( 19584346) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Coronary heart disease ( 21378990) Metabolite levels (5-HIAA) ( 23319000) Schizophrenia ( 25056061 29483656 30285260) Type 2 diabetes ( 20174558)	Asthma ( 31619474)
Interacting Genes		3 interacting genes: AKT1 APP RNF41	42 interacting genes: ADRB2 AP2S1 APP ARL6IP4 ASB6 BIRC6 C1orf109 ENOPH1 ERBB3 ERBB4 IRS4 ISCA2 KDM3B LEPR LZTS2 MAGEL2 MARK2 MEOX2 MNAT1 MTNR1A MTNR1B MTURN N4BP3 RAD23A RFC4 RNF166 RRM2B SRR TCEANC TRIM32 TRIM8 TSG101 TTC1 UBASH3A UBASH3B UBE2D3 UBE2K UBE2U UBE2Z USP8 VPS52 ZAP70
Entrez ID		63826	10193
HPRD ID		10451	11520
Ensembl ID		ENSG00000167720	ENSG00000181852
Uniprot IDs		Q3ZK31 Q8N3F4 Q9GZT4	A0A024RB33 Q9H4P4
PDB IDs		3L6B 3L6R 5X2L 6SLH	2FZP 2GWF
Enriched GO Terms of Interacting Partners?
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