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CCL19 and GALT
Data Source:
BioGRID
(affinity chromatography technology)
CCL19
GALT
Description
C-C motif chemokine ligand 19
galactose-1-phosphate uridylyltransferase
Image
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Cytoplasm
Golgi Apparatus
Cytosol
Molecular Function
Protein Binding
Chemokine Activity
CCR7 Chemokine Receptor Binding
CCR10 Chemokine Receptor Binding
Chemokine Receptor Binding
CCR Chemokine Receptor Binding
Protein Binding
UDP-glucose:hexose-1-phosphate Uridylyltransferase Activity
Zinc Ion Binding
Biological Process
Establishment Of T Cell Polarity
Immunological Synapse Formation
Dendritic Cell Chemotaxis
Myeloid Dendritic Cell Chemotaxis
Monocyte Chemotaxis
Positive Regulation Of Dendritic Cell Antigen Processing And Presentation
Cellular Calcium Ion Homeostasis
Inflammatory Response
Immune Response
Cell Communication
G Protein-coupled Receptor Signaling Pathway
Activation Of JUN Kinase Activity
Response To Virus
Positive Regulation Of Glycoprotein Biosynthetic Process
Cytokine-mediated Signaling Pathway
Neutrophil Chemotaxis
T Cell Costimulation
Positive Regulation Of Interleukin-1 Beta Production
Positive Regulation Of Interleukin-12 Production
Positive Regulation Of Tumor Necrosis Factor Production
Response To Prostaglandin E
Positive Regulation Of T Cell Proliferation
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of GTPase Activity
Positive Regulation Of Phosphatidylinositol 3-kinase Activity
Positive Regulation Of T-helper 1 Cell Differentiation
Positive Regulation Of Endocytosis
Positive Regulation Of Protein Kinase Activity
Positive Regulation Of JNK Cascade
Lymphocyte Chemotaxis
Positive Regulation Of Receptor-mediated Endocytosis
Cell Maturation
Positive Regulation Of Chemotaxis
Release Of Sequestered Calcium Ion Into Cytosol
Positive Regulation Of Protein Kinase B Signaling
Regulation Of Cell Projection Assembly
Chemokine-mediated Signaling Pathway
Positive Regulation Of ERK1 And ERK2 Cascade
Cellular Response To Interferon-gamma
Cellular Response To Interleukin-1
Cellular Response To Tumor Necrosis Factor
Response To Nitric Oxide
Positive Regulation Of Neutrophil Chemotaxis
Mature Conventional Dendritic Cell Differentiation
Cellular Response To Virus
Positive Regulation Of NIK/NF-kappaB Signaling
Positive Regulation Of Cell Motility
Positive Regulation Of Dendritic Cell Dendrite Assembly
Negative Regulation Of Dendritic Cell Apoptotic Process
UDP-glucose Metabolic Process
Galactose Metabolic Process
UDP-glucose Catabolic Process
Galactose Catabolic Process
Galactose Catabolic Process Via UDP-galactose
Pathways
Chemokine receptors bind chemokines
G alpha (i) signalling events
Interleukin-10 signaling
Defective GALT can cause Galactosemia
Galactose catabolism
Drugs
Diseases
Galactosemia
GWAS
Metabolite levels (
23823483
)
Rheumatoid arthritis (
30423114
24390342
)
Interacting Genes
8 interacting genes:
ACKR2
ACKR4
CCL22
CCR10
CCR7
CXCL13
MEOX2
PF4V1
7 interacting genes:
GRPEL1
KRTAP6-2
NQO1
TNK2
TRIP13
UBTD2
VAC14
Entrez ID
6363
2592
HPRD ID
03750
06106
Ensembl ID
ENSG00000172724
ENSG00000213930
Uniprot IDs
Q6IBD6
Q99731
A0A0S2Z3Y7
B2RAT6
P07902
PDB IDs
2MP1
1R3A
5IN3
6GQD
Enriched GO Terms of Interacting Partners
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