MRPL12 and NBL1

Data Source:
BioGRID (two hybrid)

		MRPL12	NBL1
Description		mitochondrial ribosomal protein L12	NBL1, DAN family BMP antagonist
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Large Ribosomal Subunit	Extracellular Space
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding	Protein Binding Morphogen Activity BMP Binding Identical Protein Binding Receptor Ligand Activity
	Biological Process	Mitochondrial Transcription Positive Regulation Of Transcription, DNA-templated Mitochondrial Translational Elongation Mitochondrial Translational Termination	Signal Transduction Nervous System Development Animal Organ Morphogenesis Negative Regulation Of BMP Signaling Pathway Sequestering Of BMP In Extracellular Matrix Sequestering Of BMP From Receptor Via BMP Binding Positive Regulation Of Neuron Differentiation Determination Of Dorsal Identity Neuron Projection Morphogenesis Negative Regulation Of Monocyte Chemotaxis
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Drugs
Diseases
GWAS		LDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Refractive error ( 32231278) Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931)	Blood protein levels ( 30072576) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Bronchopulmonary dysplasia in preterm infants ( 30113228) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Serum thyroid-stimulating hormone levels ( 24852370) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		24 interacting genes: CBX3 COX6A2 EFCAB2 EFEMP2 EXOC3L2 FBLN1 KRTAP10-1 MAPRE3 MICOS10-NBL1 MORF4L1 MORF4L2 NBL1 NTAQ1 NTM OLIG1 POLR1D PPP1R16A RARG SAT1 SEPTIN1 TMEM51 TRIM59 TXNDC9 ZNF76	14 interacting genes: BAG6 DPEP2NB HPCAL1 KRTAP11-1 LRIG1 MEOX2 MRPL12 NCALD NCS1 PLA2G2F SLPI UBQLN1 UBQLN2 ZMIZ2
Entrez ID		6182	4681
HPRD ID		03849	09001
Ensembl ID		ENSG00000262814	ENSG00000158747
Uniprot IDs		P52815	A0A087WTY6 P41271
PDB IDs		6VLZ 6VMI 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG	4X1J 4YU8
Enriched GO Terms of Interacting Partners?
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