RPGR and SLC9A7

Data Source:
HPRD (two hybrid)

		RPGR	SLC9A7
Description		retinitis pigmentosa GTPase regulator	solute carrier family 9 member A7
Image			No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Golgi Apparatus Centrosome Ciliary Basal Body Sperm Flagellum	Golgi Membrane Trans-Golgi Network Plasma Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Recycling Endosome Recycling Endosome Membrane
	Molecular Function	RNA Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding	Protein Binding Sodium:proton Antiporter Activity Potassium:proton Antiporter Activity
	Biological Process	Intracellular Protein Transport Visual Perception Intraciliary Transport Regulation Of Catalytic Activity Response To Stimulus Cilium Assembly	Ion Transport Regulation Of PH Regulation Of Intracellular PH Potassium Ion Transmembrane Transport Anion Transmembrane Transport Sodium Ion Import Across Plasma Membrane Proton Transmembrane Transport Regulation Of Golgi Lumen Acidification
Pathways			Sodium/Proton exchangers
Drugs
Diseases		Macular degeneration, including: Age-related macular degeneration (ARMD); Patterned dystrophy of retinal pigment epithelium (PDREP); Retinal macular dystrophy 2 (MCDR2); X-linked atrophic macular degeneration (MDXLA) Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD) Retinitis pigmentosa (RP)
GWAS			Hematocrit ( 32888494) Hemoglobin ( 32888494) Lymphocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) White blood cell count ( 32888494)
Interacting Genes		14 interacting genes: DCTN1 DCTN2 HOMEZ IFT88 KIF3A KIFAP3 NPM1 PDE6D RPGRIP1 SLC25A10 SMC1A SMC3 TUBG1 YWHAE	4 interacting genes: GPR35 SCAMP1 SCAMP2 SCAMP5
Entrez ID		6103	84679
HPRD ID		02425	02297
Ensembl ID		ENSG00000156313	ENSG00000065923
Uniprot IDs		Q92834	A0A024R176 A0A087WXD1 Q96T83
PDB IDs		4JHN 4JHP 4QAM
Enriched GO Terms of Interacting Partners?
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