FKBP10 and ELN

Data Source:
HPRD (in vitro, in vivo)

		FKBP10	ELN
Description		FKBP prolyl isomerase 10	elastin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrial Intermembrane Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Membrane	Extracellular Region Extracellular Matrix Collagen-containing Extracellular Matrix Elastic Fiber
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Calcium Ion Binding Protein Binding FK506 Binding	Extracellular Matrix Structural Constituent Protein Binding Extracellular Matrix Constituent Conferring Elasticity Extracellular Matrix Binding
	Biological Process	Protein Peptidyl-prolyl Isomerization In Utero Embryonic Development Peptidyl-lysine Hydroxylation Peptidyl-proline Modification Collagen Fibril Organization Aorta Morphogenesis Wound Healing Extracellular Matrix Assembly	Outflow Tract Morphogenesis Aortic Valve Morphogenesis Skeletal Muscle Tissue Development Respiratory Gaseous Exchange By Respiratory System Blood Circulation Animal Organ Morphogenesis Extracellular Matrix Organization Regulation Of Actin Filament Polymerization Stress Fiber Assembly Regulation Of Smooth Muscle Cell Proliferation
Pathways			Degradation of the extracellular matrix Elastic fibre formation Molecules associated with elastic fibres Molecules associated with elastic fibres
Drugs			Rofecoxib
Diseases		Bruck syndrome	Congenital supravalvar aortic stenosis Cutis laxa, including: Autosomal dominant cutis laxa (ADCL); Autosomal recessive cutis laxa I (ARCL1); Autosomal recessive cutis laxa II (ARCL2); X-linked recessive cutis laxa (XRCL); Wrinkly skin syndrome
GWAS		Eosinophil counts ( 32888494)	Diverticular disease ( 30177863) Height ( 31562340)
Interacting Genes		3 interacting genes: CDC42 ELN SLC2A4	22 interacting genes: ASS1 BGN CKMT2 CLU DCN ELANE FBLN1 FBLN2 FBN1 FBN2 FCN1 FKBP10 LGALS3 LOX LOXL1 LYZ MAGEH1 MFAP2 MTDH NID2 PRTN3 SPINK1
Entrez ID		60681	2006
HPRD ID		09522	00556
Ensembl ID		ENSG00000141756	ENSG00000049540
Uniprot IDs		A0A024R1W3 Q658U4 Q8NAG5 Q96AY3	B3KRT8 B4E3S4 E7EN65 E7ENM0 G3V0G6 G5E950 P15502 Q59H17 Q6ZUN2 Q8NBI4
PDB IDs
Enriched GO Terms of Interacting Partners?
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