HAPLN2 and VWC2

Data Source:
BioGRID (two hybrid)

		HAPLN2	VWC2
Description		hyaluronan and proteoglycan link protein 2	von Willebrand factor C domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Matrix	Basement Membrane Interstitial Matrix Extracellular Space AMPA Glutamate Receptor Complex Synapse
	Molecular Function	Protein Binding Hyaluronic Acid Binding	Molecular_function Protein Binding
	Biological Process	Skeletal System Development Cell Adhesion Central Nervous System Development Establishment Of Blood-nerve Barrier Extracellular Matrix Assembly	Positive Regulation Of Cell-substrate Adhesion Negative Regulation Of BMP Signaling Pathway Positive Regulation Of Neuron Differentiation
Pathways
Drugs
Diseases
GWAS			Blood protein levels ( 30072576 29875488) Body mass index ( 28892062 25673413) Lung cancer in never smokers ( 28604730) Neurological blood protein biomarker levels ( 31320639) Post bronchodilator FEV1/FVC ratio ( 26634245) Pursuit maintenance gain ( 29064472) Serum thyroid-stimulating hormone levels ( 25436638)
Interacting Genes		47 interacting genes: ASB13 BANP CCDC125 CIDEB EXOSC8 FHL3 FHL5 FNDC3B GOLGA6L9 GPRIN2 KRT15 KRT27 KRT31 KRT33B KRT34 KRT35 KRT37 KRT40 KRT85 KRTAP10-8 KRTAP19-5 KRTAP2-3 KRTAP2-4 KRTAP6-2 KRTAP6-3 KRTAP9-2 MDFI MID2 MTUS2 NBPF19 NOTCH2NLA OIP5 PFDN5 PM20D2 PNMA1 PNMA2 PPP1R16B PSTPIP1 SEC13 SSC4D TFCP2 TRIM23 TRIM27 VWC2 ZMYND12 ZNF438 ZNF655	57 interacting genes: ABHD15 ADAMTSL4 ATPAF2 CAMLG CATSPER1 CNNM3 CRY2 CYSRT1 ENKD1 FAM90A1 FBXW5 FUCA2 GET3 GNE HAPLN2 HOXA1 HPCA HPCAL1 KANK2 KPRP KRTAP10-8 KRTAP13-2 KRTAP13-3 KRTAP2-3 KRTAP2-4 KRTAP5-9 LCE1A LCE1C LCE1F LCE2C LCE2D LCE3A LCE3D LCE3E LCE4A NTM OTX1 PFKFB1 POU4F2 PRPF31 SCNM1 SGTB SHFL SPRY1 TRAPPC14 UBQLN1 UBQLN2 VASN YY1 ZNF319 ZNF417 ZNF490 ZNF497 ZNF587 ZNF696 ZNF774 ZNF837
Entrez ID		60484	375567
HPRD ID		17088	18271
Ensembl ID		ENSG00000132702	ENSG00000188730
Uniprot IDs		Q9GZV7	Q2TAL6
PDB IDs
Enriched GO Terms of Interacting Partners?
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