RFXAP and RFXANK

Data Source:
HPRD (in vivo, in vitro)

		RFXAP	RFXANK
Description		regulatory factor X associated protein	regulatory factor X associated ankyrin containing protein
Image
GO Annotations	Cellular Component	Nucleus Nuclear Speck RNA Polymerase II Transcription Regulator Complex	Nucleus Nucleoplasm Cytosol Intercellular Bridge RNA Polymerase II Transcription Regulator Complex
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Histone Deacetylase Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription By RNA Polymerase II Ras Protein Signal Transduction Regulation Of Gene Expression Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases		Bare lymphocyte syndrome (BLS) type2 Combined immunodeficiencies (CIDs), including the following nine diseases: X-linked hyper IgM syndrome; CD40 deficiency hyper IgM syndrome; Purine nucleoside phosphorylase (PNP) deficiency; Omenn syndrome; MHC deficiency (HLA-class I); MHC deficiency (HLA-class II); Zap-70 deficiency; p56 Lck deficiency; CD8 deficiency	Bare lymphocyte syndrome (BLS) type2 Combined immunodeficiencies (CIDs), including the following nine diseases: X-linked hyper IgM syndrome; CD40 deficiency hyper IgM syndrome; Purine nucleoside phosphorylase (PNP) deficiency; Omenn syndrome; MHC deficiency (HLA-class I); MHC deficiency (HLA-class II); Zap-70 deficiency; p56 Lck deficiency; CD8 deficiency
GWAS		Metabolite levels ( 23823483) Perioperative myocardial infarction in coronary artery bypass surgery ( 25948407)	Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Bipolar II disorder ( 31043756) Refractive error ( 32231278)
Interacting Genes		4 interacting genes: EPS8 RFX5 RFXANK SMARCA4	6 interacting genes: CIITA HDAC4 HDAC5 RAF1 RFX5 RFXAP
Entrez ID		5994	8625
HPRD ID		03515	04435
Ensembl ID		ENSG00000133111	ENSG00000064490
Uniprot IDs		O00287	A0A024R7M1 A0A024R7P0 O14593
PDB IDs		2KW3	3UXG 3V30 6MEW
Enriched GO Terms of Interacting Partners?
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