RDH5 and NAB2

Data Source:
BioGRID (affinity chromatography technology)

		RDH5	NAB2
Description		retinol dehydrogenase 5	NGFI-A binding protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Integral Component Of Membrane Cell Body	Nucleus
	Molecular Function	Retinol Dehydrogenase Activity Protein Homodimerization Activity Androsterone Dehydrogenase Activity Androstan-3-alpha,17-beta-diol Dehydrogenase Activity	Transcription Coregulator Activity Transcription Corepressor Activity Protein Binding Transcription Factor Binding Identical Protein Binding
	Biological Process	Retinoid Metabolic Process Visual Perception Steroid Metabolic Process Retinol Metabolic Process Response To Stimulus	Endochondral Ossification Regulation Of Transcription, DNA-templated Schwann Cell Differentiation Negative Regulation Of Transcription By RNA Polymerase III Myelination Regulation Of Epidermis Development Positive Regulation Of Tau-protein Kinase Activity
Pathways		Retinoid cycle disease events The canonical retinoid cycle in rods (twilight vision) RA biosynthesis pathway	NGF-stimulated transcription NGF-stimulated transcription EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs		NADH Vitamin A
Diseases		Familial flecked retina syndrome, including: Doyne honeycomb degeneration of retina (DHRD); Basal laminar drusen (BLD); Fundus albipunctatus (FA); Retinitis punctata albescens (RPA); Bietti crystalline corneoretinal dystrophy (BCD)
GWAS		Advanced age-related macular degeneration ( 26691988) High myopia ( 31816047) Macular thickness ( 30535121) Myopia ( 27182965) Refractive error ( 23396134) Spherical equivalent (joint analysis main effects and education interaction) ( 27020472) Spherical equivalent or myopia (age of diagnosis) ( 29808027)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31361310 31959851 31619474 29273806) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Asthma or allergic disease (pleiotropy) ( 29785011) Bipolar disorder ( 31043756) IgE levels ( 22075330) Schizophrenia ( 25056061 29483656)
Interacting Genes		3 interacting genes: ORC4 RGR RLBP1	80 interacting genes: ANK3 ANKRD11 CBX8 CCDC187 CCDC33 CCDC57 CCHCR1 CDC23 CTAG1A CTAG1B CTNNA3 CWF19L2 DDX6 DGCR6 DGCR6L DRG2 EGR1 EGR2 ELOA ENKD1 EXOC8 FAM9A GCC1 GOLGA6L9 HSF2BP JAKMIP2 KIF9 KIFC3 KRT34 KRT40 KRTAP10-3 KRTAP10-8 LENG1 LMNA LNX1 MAPK3 MCM7 MCRS1 MDFI MORF4L1 MORF4L2 NDOR1 NEDD9 NME7 NOTCH2NLA NTAQ1 PHF1 PHOSPHO2 PIK3R3 PIN1 PLOD3 PRKAA2 PRKAB2 PSMA1 QARS1 RBPMS RFC5 RINT1 SCNM1 SMARCD1 SORBS3 SPG21 SUMO1P1 TCEA2 TCEANC TCHP TGIF2LY TLE5 TRAF2 TRIM23 TSGA10 TSGA10IP TTC19 USP2 UTP14C ZBED8 ZMAT2 ZMYND12 ZMYND19 ZNF417
Entrez ID		5959	4665
HPRD ID		03370	03854
Ensembl ID		ENSG00000135437	ENSG00000166886
Uniprot IDs		A0A024RB18 Q92781	Q15742
PDB IDs
Enriched GO Terms of Interacting Partners?
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