RAB5C and ALS2CL

Data Source:
BioGRID (two hybrid)

		RAB5C	ALS2CL
Description		RAB5C, member RAS oncogene family	ALS2 C-terminal like
Image			No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Endosome Early Endosome Lipid Droplet Plasma Membrane Endomembrane System Endocytic Vesicle Early Endosome Membrane Azurophil Granule Membrane Melanosome Extracellular Exosome	Cytosol
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding	GTPase Activator Activity Protein Binding Identical Protein Binding
	Biological Process	Intracellular Protein Transport Endocytosis Regulation Of Endocytosis Neutrophil Degranulation Plasma Membrane To Endosome Transport	Endosome Organization Positive Regulation Of GTPase Activity
Pathways		Golgi Associated Vesicle Biogenesis Neutrophil degranulation TBC/RABGAPs Clathrin-mediated endocytosis RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Fibrinogen levels ( 28107422 26561523) Mean corpuscular volume ( 32888494) Medication use (thyroid preparations) ( 31015401) Vitiligo ( 27723757) vWF and FVIII levels ( 30586737) White blood cell count ( 32888494)
Interacting Genes		15 interacting genes: ALS2CL APP APPL2 EEA1 ERBB2 GLP1R HRAS INCA1 RABAC1 RBSN RIN2 RIN3 SGSM3 TBC1D15 TBC1D17	7 interacting genes: EEF1AKMT3 PPP1R32 RAB22A RAB31 RAB5A RAB5C RSPH14
Entrez ID		5878	259173
HPRD ID		04947	10643
Ensembl ID		ENSG00000108774	ENSG00000178038
Uniprot IDs		A0A024R1U4 P51148	A0A024R2U1 Q60I27
PDB IDs		4KYI
Enriched GO Terms of Interacting Partners?
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