MYL7 and PPM1B

Data Source:
BioGRID (two hybrid)

		MYL7	PPM1B
Description		myosin light chain 7	protein phosphatase, Mg2+/Mn2+ dependent 1B
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Myosin Complex A Band	Nucleus Nucleolus Cytosol Membrane
	Molecular Function	Calcium Ion Binding Protein Binding	Magnesium Ion Binding Protein Serine/threonine Phosphatase Activity Protein Binding Manganese Ion Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process	Muscle Contraction	Protein Dephosphorylation N-terminal Protein Myristoylation Negative Regulation Of Interferon-beta Production Peptidyl-threonine Dephosphorylation Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Defense Response To Virus Positive Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of NIK/NF-kappaB Signaling
Pathways		Smooth Muscle Contraction	ISG15 antiviral mechanism
Drugs
Diseases
GWAS		Offspring birth weight ( 31043758) Type 2 diabetes ( 32499647)	Alcohol consumption (drinks per week) ( 30643258) Chronotype ( 30696823) Estimated glomerular filtration rate ( 31152163) Height ( 23563607 31562340) Metabolite levels ( 23823483) Morning person ( 30696823) Number of sexual partners ( 30643258) Refractive error ( 32231278) Risk-taking tendency (4-domain principal component model) ( 30643258)
Interacting Genes		7 interacting genes: MCCD1 MEOX2 POU6F2 PPM1B PSORS1C2 SUOX TOX4	21 interacting genes: AATK CDK2 CDK6 ECHS1 EGFR ERBB3 ERBB4 IKBKB IKBKG KDR MAD2L2 MAP3K7 MSN MYL7 PPARG PTK7 ROR1 ROR2 RYK SIRPA VAV2
Entrez ID		58498	5495
HPRD ID		10105	04796
Ensembl ID		ENSG00000106631	ENSG00000138032
Uniprot IDs		Q01449	O75688
PDB IDs			2P8E
Enriched GO Terms of Interacting Partners?
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