PVT1 and RPS16

Data Source:
BioGRID (unspecified method)

		PVT1	RPS16
Description		Pvt1 oncogene	ribosomal protein S16
Image		No pdb structure
GO Annotations	Cellular Component		Nucleoplasm Cytosol Focal Adhesion Small Ribosomal Subunit Membrane Cytosolic Small Ribosomal Subunit Extracellular Exosome
	Molecular Function		RNA Binding Structural Constituent Of Ribosome Protein Binding
	Biological Process		Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Processing Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription Ribosomal Small Subunit Biogenesis
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Allergic sensitization ( 30013184 23817571) Amyotrophic lateral sclerosis (sporadic) ( 24529757) B-cell malignancies (chronic lymphocytic leukemia, Hodgkin lymphoma or multiple myeloma) (pleiotropy) ( 28112199) Basophil count ( 32888494) Celiac disease and Rheumatoid arthritis ( 26546613) Crohn's disease ( 32581322) Diffuse large B cell lymphoma ( 25261932) End-stage renal disease ( 17395743) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Follicular lymphoma ( 25279986) Graft survival time in renal transplantation (donor effect) x APOL1 genotype interaction ( 32080893) Hematocrit ( 32888494 27863252) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Hodgkin's lymphoma ( 21037568) Immunoglobulin A ( 20694011) Lung cancer ( 28604730) Lymphocyte counts ( 32888494 27863252) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean spheric corpuscular volume ( 32888494) Medication use (adrenergics, inhalants) ( 31015401) Medication use (thyroid preparations) ( 31015401) Metabolite levels (Dihydroxy docosatrienoic acid) ( 23934736) Monocyte count ( 32888494) Multiple sclerosis ( 31604244 21833088) Neutrophil count ( 32888494) Neutrophil percentage of granulocytes ( 27863252) Neutrophil percentage of white cells ( 32888494) Orofacial clefts ( 19270707) Pancreatic cancer ( 25086665) Platelet count ( 32888494) Plateletcrit ( 32888494 27863252) Psychosis (atypical) ( 24132900) Renal cell carcinoma ( 24220699) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Rheumatoid arthritis ( 30423114 24390342) Seasonality ( 25562672) Selective IgA deficiency ( 27723758) Sum eosinophil basophil counts ( 27863252) Systemic lupus erythematosus ( 28714469) Type 2 diabetes ( 30297969) Urinary bladder cancer ( 24861552) Urinary calcium excretion ( 31993563) Waist-hip ratio ( 28552196) White blood cell count ( 32888494 27863252)
Interacting Genes		5 interacting genes: ERG KRT9 POTEKP RBM25 RPS16	4 interacting genes: APP DUX4 NDRG1 PVT1
Entrez ID		5820	6217
HPRD ID			04724
Ensembl ID		ENSG00000249859	ENSG00000105193
Uniprot IDs			M0R210 P62249
PDB IDs			4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6EK0 6FEC 6G18 6G4S 6G4W 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6XA1 6Y0G 6Y2L 6Y57 6YBS 6Z6L 6Z6M 6Z6N 6ZLW 6ZM7 6ZME 6ZMI 6ZMO 6ZMT 6ZMW 6ZN5 6ZOJ 6ZOL 6ZON 6ZP4 6ZVH 6ZVJ 7A09 7K5I
Enriched GO Terms of Interacting Partners?
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