PURB and MIR34B

Data Source:
BioGRID (unspecified method)

		PURB	MIR34B
Description		purine rich element binding protein B	microRNA 34b
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Single-stranded DNA Binding RNA Binding MRNA Binding Protein Binding Transcription Factor Binding Purine-rich Negative Regulatory Element Binding SMAD Binding	MRNA Binding Involved In Posttranscriptional Gene Silencing
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Cell Population Proliferation Cell Differentiation Regulation Of Myeloid Cell Differentiation	Gene Silencing By MiRNA Negative Regulation Of Protein Kinase B Signaling Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Negative Regulation Of Sprouting Angiogenesis Positive Regulation Of Connective Tissue Replacement
Pathways
Drugs
Diseases
GWAS		Platelet count ( 27863252)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma or allergic disease (pleiotropy) ( 29785011) Bipolar disorder ( 31043756)
Interacting Genes		22 interacting genes: AP1M1 CSNK2A1 IL7R LNX1 MBD2 MIR128-1 MIR128-2 MIR25 MIR29C MIR31 MIR34B MIR363 MIR7-1 MIR7-3 MIR9-2 MIRLET7A3 MIRLET7G MIRLET7I NABP1 PCDHB14 PURA ZNF497	109 interacting genes: ADARB1 AIMP1 AIMP2 APOBEC3B AQR ATXN2 ATXN2L C1QBP CDC5L CELF1 CELF2 CPSF1 CPSF7 DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EIF2AK2 EPRS1 ERAL1 ESRP1 FAM98A FIP1L1 FUS G3BP2 HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI1 MSI2 MTERF3 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PDCD11 PIP5K1A PLOD1 PTBP1 PTBP3 PTCD3 PUF60 PURA PURB QARS1 QKI RARS1 RBFOX2 RBM14 RBM4 RBM45 RBM4B RTCA RTCB SART3 SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYNCRIP TAF15 TENT2 TRA2A TRA2B TRIM56 U2SURP UPF1 USP36 UTP20 WDR33 XAB2 YBX1 YBX2 YBX3 ZFR ZNF346
Entrez ID		5814	407041
HPRD ID		12325
Ensembl ID		ENSG00000146676	ENSG00000207811
Uniprot IDs		Q96QR8
PDB IDs
Enriched GO Terms of Interacting Partners?
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