PTPRF and PTPRD

  • Data Source:
  • BioGRID (imaging technique)
  • HPRD (in vivo)

PTPRF

PTPRD
Description protein tyrosine phosphatase receptor type F protein tyrosine phosphatase receptor type D
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adventurousness ( 30643258)
  • Amyotrophic lateral sclerosis (age of onset) ( 22959728)
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Attention deficit hyperactivity disorder ( 30478444)
  • Attention deficit hyperactivity disorder or cannabis use ( 30610198)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Coffee consumption ( 31046077)
  • Cognitive ability (MTAG) ( 29186694)
  • Educational attainment ( 27046643)
  • General cognitive ability ( 29844566)
  • General risk tolerance (MTAG) ( 30643258)
  • Household income (MTAG) ( 31844048)
  • Intake of total sugars ( 31005972)
  • Intelligence (MTAG) ( 29326435)
  • Mean reticulocyte volume ( 32888494)
  • Refractive error ( 32231278)
  • Schizophrenia ( 28991256 25056061 29483656 30285260)
  • Smoking initiation ( 30617275)
  • Smoking initiation (ever regular vs never regular) ( 30679032)
  • Stroke ( 29531354)
  • Urate levels ( 31578528)
  • Adult body size ( 32376654)
  • Age-related cognitive decline (language) (slope of z-scores) ( 30954325)
  • Airflow obstruction ( 22837378)
  • Anxiety and major depressive disorder ( 24047446)
  • Aspartate aminotransferase levels in non-alcoholic fatty liver disease ( 31311600)
  • Attention deficit hyperactivity disorder and conduct disorder ( 18951430)
  • Bitter alcoholic beverage consumption ( 31046077)
  • Body mass index (change over time) in gastrointestinal cancer or chronic obstructive pulmonary disease ( 28044437)
  • Cardiac Troponin-T levels ( 31014085)
  • Cardiorespiratory fitness (800m run time) ( 32572135)
  • Cerebrospinal P-tau181p levels ( 28247064)
  • Chronotype ( 30696823)
  • Diastolic blood pressure ( 30224653)
  • Early age at menarche ( 29773799)
  • Endometrial cancer (endometrioid histology) ( 30093612)
  • Endometriosis or endometrial cancer (pleiotropy) ( 29608257)
  • Epilepsy (remission after treatment) ( 23962720)
  • Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer ( 28429243)
  • Gait rhythm ( 26219847)
  • Glycine levels ( 31070104)
  • Gout ( 22179738)
  • Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
  • Heel bone mineral density ( 30598549)
  • Immune response to measles-mumps-rubella vaccine ( 24811271)
  • Intracranial aneurysm ( 29531279)
  • Lean body mass ( 28552196)
  • Loneliness ( 27629369)
  • Loneliness (linear analysis) ( 27629369)
  • Loneliness (multivariate analysis) ( 27629369)
  • Low susceptibility to hepatitis C infection ( 31206233)
  • Menarche (age at onset) ( 29773799 25231870)
  • Metabolite levels ( 23823483)
  • Midgestational circulating levels of PCBs (fetal genetic effect) ( 28235828)
  • Moderate-to-late spontaneous preterm birth ( 31194736)
  • Modic changes ( 30808802)
  • Mood instability ( 29187730)
  • Morning person ( 30696823)
  • Myopia (pathological) ( 23049088)
  • Non-alcoholic fatty liver disease activity score in non-alcoholic fatty liver disease ( 31311600)
  • Non-response to antidepressants and depression ( 27622933)
  • Obesity-related traits ( 23251661)
  • Obsessive-compulsive disorder ( 24821223)
  • Opioid use cessation ( 31936517)
  • Palmitic acid (16:0) levels ( 23362303)
  • Parkinson's disease progression (motor) ( 33111402)
  • Partial epilepsies ( 20522523)
  • Pelvic organ prolapse (moderate/severe) ( 26545240)
  • Personality dimensions ( 23903073)
  • Pit-and-Fissure caries ( 24556642)
  • Plasma clusterin levels ( 26545630)
  • Platelet aggregation ( 20526338)
  • Post bronchodilator FEV1 ( 26634245)
  • Post bronchodilator FEV1 in COPD ( 26634245)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)
  • Pulse pressure ( 27841878)
  • Pursuit maintenance gain ( 29064472)
  • Resistant hypertension ( 30237584)
  • Resting-state electroencephalogram vigilance ( 29703947)
  • Restless legs syndrome ( 18660810 29029846 21779176)
  • Short-term memory (digit-span task) ( 30741946)
  • Subcutaneous adipose tissue ( 26480920)
  • Systolic blood pressure ( 30224653 27841878)
  • Temperament ( 22832960)
  • Third ventricle volume ( 31530798)
  • Type 2 diabetes ( 21647700 20174558)
  • Waist-hip ratio ( 28552196)
  • Waist-to-hip ratio adjusted for BMI x sex interaction ( 26426971)
  • White matter hyperintensities in ischemic stroke ( 26674333)
Interacting Genes 59 interacting genes: ACAN ACAT1 ACTB ARHGEF11 ARHGEF12 ARHGEF2 ATP5F1A BCAR1 CAV1 CBR1 CDH1 CREBBP CTNNB1 DEPDC1B DIAPH1 EEF1A1 EEF1G FRS2 FYN GALNT1 GAPDH GPC4 HSP90AA1 HSPA1A HSPA1L HSPA5 HSPA8 HSPA9 INSR IRS1 IRS2 JUP LACTB LCK LDHA LDHB NCAN NID1 PPFIA1 PPFIA2 PPFIA3 PRPF40A PTPRA PTPRD PTPRZ1 RAP1GDS1 RET RHOA ROCK2 SEMG1 SEMG2 SEPTIN9 SKIL SOWAHC TRIO TUBA1B TUBB4B VCAN ZNF512B 34 interacting genes: ABLIM1 AURKA BMX CSNK1D CSNK1E DDX17 DDX54 EPHA8 GPC4 IL1RAP IRS1 MARK2 MATK MTNR1A MTNR1B MTSS1 NEK1 NEK2 NEK6 PAK6 PLK1 PPFIA1 PPFIA2 PPFIA3 PTPRA PTPRE PTPRF PTPRS SCEL SLAIN2 SLITRK1 SMTNL2 TBK1 TSSK2
Entrez ID 5792 5789
HPRD ID 01552 03358
Ensembl ID ENSG00000142949 ENSG00000153707
Uniprot IDs G1UI20 P10586 P23468 Q2HXI4 Q3KPI9 Q59H90
PDB IDs 1LAR 2DJU 2DN7 2EDX 2EDY 2YD5 2YD8 4N5U 6KR4 6TPT 6TPU 6TPV 6TPW 1X5Z 2DLH 2YD6 2YD7 4RCA 5WY8 5XNP
Enriched GO Terms of Interacting Partners?
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