ZNF410 and OSM

Data Source:
BioGRID (two hybrid)

		ZNF410	OSM
Description		zinc finger protein 410	oncostatin M
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Extracellular Region Extracellular Space
	Molecular Function	Transcription Coregulator Activity Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Cytokine Activity Oncostatin-M Receptor Binding Protein Binding Growth Factor Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Positive Regulation Of Acute Inflammatory Response Immune Response Multicellular Organism Development Positive Regulation Of Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Cytokine-mediated Signaling Pathway Positive Regulation Of Interleukin-17 Production Positive Regulation Of Peptidyl-serine Phosphorylation Oncostatin-M-mediated Signaling Pathway Regulation Of Growth Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Positive Regulation Of MAPK Cascade Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Hormone Secretion Positive Regulation Of Inflammatory Response Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Cell Division Positive Regulation Of Protein Kinase B Signaling Regulation Of Hematopoietic Stem Cell Differentiation
Pathways			Interleukin-4 and Interleukin-13 signaling IL-6-type cytokine receptor ligand interactions
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Serum uric acid levels ( 29559957)	Coronary artery disease ( 29212778 33020668) Delirium ( 29631748) Heel bone mineral density ( 30598549) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Inflammatory bowel disease ( 23128233) Nephropathy ( 21399633) Suicidal ideation ( 30145303) Tonsillectomy ( 27941131)
Interacting Genes		54 interacting genes: ABHD8 APP BANP BLZF1 CCNG2 CDKN2A CEP70 CSNK2B DPEP2NB DVL2 FAM9B FHL2 FSD2 GOLGA2 GOLGA6L9 HOXB2 IQUB IRAK1BP1 KRT40 LIMS1 LMO2 LMO4 LNX2 LRIF1 MEOX1 MEOX2 MID2 MTUS2 NDUFAB1 NOSIP OSM PAX6 PDE4DIP PICK1 PNMA1 POGZ POLR2G POLR2M POU6F2 PPM1K PPP1R16B PRKAR1B RAB3IP RASSF3 RCN1 RPRD1A SERTAD1 TRAF2 TRIM35 TSGA10 UHRF2 VBP1 ZNF24 ZNF397	12 interacting genes: APP COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 IL6ST LIFR OSMR TNNT1 ZNF410
Entrez ID		57862	5008
HPRD ID		18339	01300
Ensembl ID		ENSG00000119725	ENSG00000099985
Uniprot IDs		A0A024R691 Q53FM1 Q86VK4	B5MCX1 P13725
PDB IDs			1EVS
Enriched GO Terms of Interacting Partners?
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