LSM2 and LGALS7

Data Source:
BioGRID (two hybrid)

		LSM2	LGALS7
Description		LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated	galectin 7
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GO Annotations	Cellular Component	P-body Nucleus Nucleoplasm U6 SnRNP Cytoplasm Cytosol U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Precatalytic Spliceosome Catalytic Step 2 Spliceosome Lsm2-8 Complex Lsm1-7-Pat1 Complex
	Molecular Function	RNA Binding Protein Binding U6 SnRNA Binding Small GTPase Binding
	Biological Process	Spliceosomal Tri-snRNP Complex Assembly MRNA Splicing, Via Spliceosome MRNA Catabolic Process Exonucleolytic Catabolism Of Deadenylated MRNA
Pathways		mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs			Beta-D-Glucose beta-D-Galactosamine
Diseases
GWAS		Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Inflammatory bowel disease ( 28067908) Rosacea symptom severity ( 29771307) Ulcerative colitis ( 28067908)	Logical memory (immediate recall) in mild cognitive impairment ( 29274321)
Interacting Genes		37 interacting genes: BANP CBX8 CRMP1 DNAAF11 DNAJA1 ERG28 EXOSC10 GBP2 KRT13 LGALS7 LGALS7B LNX1 LSM1 LSM12 LSM3 LSM5 LSM6 LSM7 LSM8 LZTS1 MAGEA3 MAGEA6 MEOX2 PATL1 PNMA1 RALA REL RSRC1 SF3B2 SMN1 SNRPD2 SNRPE TEX11 TLE5 TRIM54 ZBTB16 ZNF408	8 interacting genes: CA12 CDC42 HSPA6 LSM2 SSBP1 TAB1 TGM5 YAF2
Entrez ID		57819	3963
HPRD ID		06282	09002
Ensembl ID		ENSG00000204392	ENSG00000205076
Uniprot IDs		Q9Y333	P47929
PDB IDs		3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9	1BKZ 2GAL 3GAL 3ZXE 3ZXF 4GAL 4UW3 4UW4 4UW5 4UW6 4XBQ 4Y26 5GAL 5H9Q 5H9S
Enriched GO Terms of Interacting Partners?
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