SUGP1 and SNRPB2

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		SUGP1	SNRPB2
Description		SURP and G-patch domain containing 1	small nuclear ribonucleoprotein polypeptide B2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex	Fibrillar Center Nucleus Nucleoplasm Spliceosomal Complex U1 SnRNP U2 SnRNP Nuclear Speck Cytoplasmic Ribonucleoprotein Granule U2-type Precatalytic Spliceosome U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	RNA Binding Protein Binding	Protein Binding U1 SnRNA Binding SnRNP Binding
	Biological Process	MRNA Splicing, Via Spliceosome	MRNA Splicing, Via Spliceosome
Pathways		mRNA Splicing - Major Pathway	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Adult body size ( 32376654) Apolipoprotein B levels ( 32203549) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Bipolar II disorder ( 31043756) Brain morphology (MOSTest) ( 32665545) Estimated glomerular filtration rate in non-diabetics ( 31451708) Fasting triglyceride levels ( 32603185) Hepatic lipid content in extreme obesity ( 25246029) LDL cholesterol ( 30275531) LDL cholesterol levels ( 32203549) LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) Nonalcoholic steatohepatitis ( 32298765) Platelet count ( 32888494) Platelet distribution width ( 32888494) Postprandial triglyceride levels ( 32603185) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656 23974872) Tea consumption ( 31046077) Triglyceride levels ( 32203549) Triglyceride levels x long total sleep time interaction (2df test) ( 31719535) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535) Type 2 diabetes ( 30054458)	Food allergy (maternal genetic effects) ( 29489655) Metabolite levels ( 23823483) Response to haloperidol in schizophrenia ( 29503163)
Interacting Genes		4 interacting genes: MIR1-1 MIRLET7G SNRPB2 U2AF2	24 interacting genes: ALAS1 CALM1 CMTM6 DHX9 ERBB3 GABPB1 GABPB2 GOLGA2 HMBOX1 HNRNPUL1 HOMEZ HTATSF1 MCM6 MTUS2 NAP1L5 PICK1 PNMA1 PTEN SMN2 SNRPA1 SUGP1 TRIM23 TRIM27 ZBTB14
Entrez ID		57794	6629
HPRD ID		10468	04628
Ensembl ID		ENSG00000105705	ENSG00000125870
Uniprot IDs		A0A024R7N3 Q8IWZ8	P08579
PDB IDs			1A9N 5MQF 5O9Z 5XJC 5YZG 5Z56 5Z57 5Z58 6AH0 6AHD 6FF7 6ICZ 6ID0 6ID1 6QDV 6QX9 6Y53 6Y5Q 7A5P
Enriched GO Terms of Interacting Partners?
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