ZNF529 and MYL2

Data Source:
BioGRID (two hybrid)

		ZNF529	MYL2
Description		zinc finger protein 529	myosin light chain 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Cytosol Cytoskeleton Actin Cytoskeleton Myosin Complex Myofibril Sarcomere A Band Cardiac Myofibril
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Metal Ion Binding	Actin Monomer Binding Calcium Ion Binding Protein Binding Structural Constituent Of Muscle Myosin Heavy Chain Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II	Regulation Of The Force Of Heart Contraction Regulation Of Striated Muscle Contraction Heart Development Muscle Filament Sliding Negative Regulation Of Cell Growth Cardiac Myofibril Assembly Ventricular Cardiac Muscle Tissue Morphogenesis Heart Contraction Positive Regulation Of The Force Of Heart Contraction
Pathways		Generic Transcription Pathway	Striated Muscle Contraction
Drugs
Diseases			Hypertrophic cardiomyopathy (HCM)
GWAS			Alcohol consumption ( 21270382) Alcohol consumption (drinkers vs non-drinkers) ( 28485404) Alcohol consumption (max-drinks) ( 29460428) Body mass index ( 24861553) Coffee consumption ( 29367735) Coronary heart disease ( 23364394) Drinking behavior ( 23364009) Gamma glutamyl transpeptidase ( 21909109) Glycemic traits ( 23575436) Gout ( 25646370) HDL cholesterol ( 21909109) HDL cholesterol levels ( 28334899) High density lipoprotein cholesterol levels ( 30718733) Metabolic syndrome ( 25705158) Metabolic syndrome (multivariate analysis) ( 29632305) Neutrophil count ( 29403010) Serum uric acid levels ( 32514006) Urate levels ( 31578528) White blood cell count ( 29403010)
Interacting Genes		2 interacting genes: MYL2 SRPK2	12 interacting genes: CDC42BPA GJB5 LRSAM1 MYOC NHP2 PAK2 PKM PPP1R12C PSORS1C2 TRIM63 USP6 ZNF529
Entrez ID		57711	4633
HPRD ID		15821	01181
Ensembl ID		ENSG00000186020	ENSG00000111245
Uniprot IDs		A0A0C4DFR4 Q6P280	P10916 Q6IB42
PDB IDs			5TBY
Enriched GO Terms of Interacting Partners?
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