QSOX1 and GREM2

Data Source:
BioGRID (affinity chromatography technology)

		QSOX1	GREM2
Description		quiescin sulfhydryl oxidase 1	gremlin 2, DAN family BMP antagonist
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Golgi Apparatus Integral Component Of Golgi Membrane Platelet Alpha Granule Lumen Specific Granule Lumen Intracellular Membrane-bounded Organelle Intercellular Bridge Extracellular Exosome Tertiary Granule Lumen	Extracellular Region Extracellular Space
	Molecular Function	Protein Disulfide Isomerase Activity Flavin-linked Sulfhydryl Oxidase Activity FAD Binding	Cytokine Activity Heparin Binding BMP Binding Receptor Ligand Activity
	Biological Process	Platelet Degranulation Protein Folding Negative Regulation Of Macroautophagy Protein Phosphopantetheinylation Neutrophil Degranulation Post-translational Protein Modification Cellular Protein Metabolic Process Extracellular Matrix Assembly	Animal Organ Morphogenesis Embryonic Body Morphogenesis Cytokine-mediated Signaling Pathway BMP Signaling Pathway Sequestering Of BMP From Receptor Via BMP Binding Regulation Of Cytokine Activity
Pathways		Platelet degranulation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Neutrophil degranulation Post-translational protein phosphorylation	Signaling by BMP
Drugs
Diseases
GWAS		Anorexia nervosa ( 23568457) Blood protein levels ( 29875488) Pulse pressure ( 30224653 30578418)	Ankle-brachial index ( 22199011) Heel bone mineral density ( 31453325) Heel bone mineral density variance ( 31453325) Immune response to smallpox vaccine (IL-6) ( 22542470) Lumbar spine bone mineral density (integral) ( 27476799) Lumbar spine bone mineral density (trabecular) ( 27476799) Mean corpuscular hemoglobin ( 32888494) Response to allopurinol in gout (change in serum uric acid levels) ( 30924126)
Interacting Genes		6 interacting genes: BEGAIN CCR1 CCR6 CHRM4 UBE2D2 UBQLN4	2 interacting genes: BMP2 BMP4
Entrez ID		5768	64388
HPRD ID		06785	16390
Ensembl ID		ENSG00000116260	ENSG00000180875
Uniprot IDs		A0A140VKE5 O00391 Q13876	Q9H772
PDB IDs		3LLI 3LLK 3Q6O 4IJ3
Enriched GO Terms of Interacting Partners?
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