CIP2A and ATIC

Data Source:
HPRD (in vivo)

		CIP2A	ATIC
Description		cellular inhibitor of PP2A	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
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GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Integral Component Of Membrane	Cytosol Plasma Membrane Membrane Extracellular Exosome
	Molecular Function	Protein Binding Protein Homodimerization Activity Cadherin Binding	IMP Cyclohydrolase Activity Phosphoribosylaminoimidazolecarboxamide Formyltransferase Activity Protein Homodimerization Activity Cadherin Binding
	Biological Process		Brainstem Development Nucleobase-containing Compound Metabolic Process 'de Novo' IMP Biosynthetic Process Nucleoside Metabolic Process Purine Ribonucleoside Monophosphate Biosynthetic Process Response To Inorganic Substance Cerebellum Development Cerebral Cortex Development Animal Organ Regeneration Dihydrofolate Metabolic Process Tetrahydrofolate Biosynthetic Process Cellular Response To Interleukin-7
Pathways			Purine ribonucleoside monophosphate biosynthesis
Drugs			Tetrahydrofolic acid Methotrexate Pemetrexed AICA ribonucleotide Guanosine-5'-Monophosphate 5-monophosphate-9-beta-D-ribofuranosyl xanthine Acid yellow 54 free acid N-[4-([(2-Amino-4-oxo-1,4-dihydropyrido[3,2-d]pyrimidin-6-yl)methyl]{(2E)-3-[4-carbamoyl-1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazol-5-yl]-2-propenoyl}amino)benzoyl]-L-glutamic acid
Diseases			AICA-ribosiduria; ATIC deficiency
GWAS			Airway imaging phenotypes ( 26030696) Metabolite levels ( 23823483)
Interacting Genes		2 interacting genes: MYC STUB1	5 interacting genes: EGFR LINC01554 MTNR1A PRNP SERPINB5
Entrez ID		57650	471
HPRD ID		11151	03434
Ensembl ID		ENSG00000163507	ENSG00000138363
Uniprot IDs		Q8TCG1	P31939 V9HWH7
PDB IDs		5UFL	1P4R 1PKX 1PL0 5UY8 5UZ0
Enriched GO Terms of Interacting Partners?
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