CASKIN1 and MINK1

Data Source:
HPRD (two hybrid)

		CASKIN1	MINK1
Description		CASK interacting protein 1	misshapen like kinase 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Membrane	Cytoplasm Golgi Apparatus Cytosol Postsynaptic Density Axon Dendrite Extracellular Exosome
	Molecular Function	Protein Binding Identical Protein Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Signal Transduction	MAPK Cascade Regulation Of Cell-matrix Adhesion Protein Phosphorylation JNK Cascade Chemical Synaptic Transmission Multicellular Organism Development Regulation Of Cell-cell Adhesion Microvillus Assembly Regulation Of Cell Migration Stress-activated Protein Kinase Signaling Cascade Actin Cytoskeleton Reorganization Activation Of Protein Kinase Activity Positive Regulation Of JNK Cascade Protein Autophosphorylation Neuron Projection Morphogenesis Dendrite Morphogenesis Positive Regulation Of P38MAPK Cascade Regulation Of AMPA Receptor Activity
Pathways			Oxidative Stress Induced Senescence
Drugs			Fostamatinib
Diseases
GWAS		Height ( 20881960)	Intracranial aneurysm ( 30823506) Lymphocyte counts ( 32888494 27863252) Lymphocyte percentage of white cells ( 32888494 27863252) Metabolite levels (lipid measures) ( 27005778) Monocyte count ( 32888494) Multiple sclerosis ( 31604244) Neutrophil percentage of white cells ( 32888494) PR interval ( 32439900)
Interacting Genes		2 interacting genes: CASK MINK1	14 interacting genes: ABI1 ACTA2 CALM3 CASKIN1 KIFAP3 MAP1B NCK1 NEDD4L NEFM PKP4 SPTBN2 TUBA1B YWHAB YWHAZ
Entrez ID		57524	50488
HPRD ID		10809	11366
Ensembl ID		ENSG00000167971	ENSG00000141503
Uniprot IDs		Q8WXD9	Q8N4C8
PDB IDs		3SEI 3SEN
Enriched GO Terms of Interacting Partners?
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