GPR158 and MASTL

Data Source:
BioGRID (two hybrid)

		GPR158	MASTL
Description		G protein-coupled receptor 158	microtubule associated serine/threonine kinase like
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Nucleus Nucleoplasm Cytoplasm Centrosome Cleavage Furrow
	Molecular Function	G Protein-coupled Receptor Activity	Protein Serine/threonine Kinase Activity ATP Binding Kinase Activity Protein Phosphatase 2A Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	G Protein-coupled Receptor Signaling Pathway Protein Localization To Plasma Membrane	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Cellular Response To DNA Damage Stimulus Peptidyl-serine Phosphorylation Negative Regulation Of Phosphoprotein Phosphatase Activity Intracellular Signal Transduction Cell Division Regulation Of Cell Cycle
Pathways			MASTL Facilitates Mitotic Progression MASTL Facilitates Mitotic Progression
Drugs
Diseases			Thrombocytopenia (THC); Familial platelet disorder with associated myeloid malignancy (FPDMM)
GWAS		Carboplatin disposition in epthelial ovarian cancer ( 29367611) Central corneal thickness ( 32528159) Cerebellum white matter volume ( 31530798) Diverticular disease ( 30177863 30661054) Energy expenditure (24h) ( 28476931) Hepatitis C (spontaneous viral clearance) ( 30593799) Immune response to smallpox vaccine (IL-6) ( 22542470) Intelligence (MTAG) ( 29326435) Intraocular pressure ( 29617998 29235454) QRS duration in Tripanosoma cruzi seropositivity ( 24324551)	Plateletcrit ( 32888494 27863252) Squamous cell lung carcinoma ( 28604730)
Interacting Genes			1 interacting genes: CDC42
Entrez ID		57512	84930
HPRD ID		13601	10499
Ensembl ID		ENSG00000151025	ENSG00000120539
Uniprot IDs		Q5T848	Q96GX5
PDB IDs			5LOH
Enriched GO Terms of Interacting Partners?
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