NLGN4X and GPR137B

Data Source:
BioGRID (proximity labelling technology)

		NLGN4X	GPR137B
Description		neuroligin 4 X-linked	G protein-coupled receptor 137B
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Integral Component Of Membrane Dendrite Synapse Excitatory Synapse Spanning Component Of Membrane Presynapse Postsynaptic Density Membrane Symmetric, GABA-ergic, Inhibitory Synapse Asymmetric, Glutamatergic, Excitatory Synapse	Lysosomal Membrane Integral Component Of Plasma Membrane Membrane
	Molecular Function	Protein Binding Chloride Ion Binding Signaling Receptor Activity Neurexin Family Protein Binding Protein Homodimerization Activity Cell Adhesion Molecule Binding Scaffold Protein Binding	Protein Binding
	Biological Process	Brainstem Development Neuron Cell-cell Adhesion Chemical Synaptic Transmission Learning Cerebellum Development Neuron Differentiation Adult Behavior Social Behavior Organ Growth Cell-cell Junction Organization Synaptic Vesicle Endocytosis Modulation Of Chemical Synaptic Transmission Synapse Organization Vocalization Behavior Negative Regulation Of Excitatory Postsynaptic Potential Postsynaptic Membrane Assembly Presynaptic Membrane Assembly Presynapse Assembly	Autophagy Regulation Of Autophagy Regulation Of Macrophage Activation Regulation Of GTPase Activity Negative Regulation Of Osteoclast Differentiation Negative Regulation Of Bone Resorption Positive Regulation Of Protein Localization To Lysosome Positive Regulation Of TORC1 Signaling
Pathways		Neurexins and neuroligins Neurexins and neuroligins
Drugs
Diseases		Non-syndromic X-linked mental retardation
GWAS		Metabolite levels ( 23823483) Schizophrenia ( 25056061 29483656)	Diastolic blood pressure ( 27841878) Metabolite levels ( 23823483) Response to antipsychotic treatment in schizophrenia (working memory) ( 21107309) Systolic blood pressure ( 27841878) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		2 interacting genes: DLG4 DLGAP2	2 interacting genes: APP TRIM32
Entrez ID		57502	7107
HPRD ID		02336	06878
Ensembl ID		ENSG00000146938	ENSG00000077585
Uniprot IDs		A0A024RBV0 A8K4S1 B3KP11 Q8N0W4	O60478
PDB IDs		2WQZ 2XB6 3BE8
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?