MIR451A and AIMP1

Data Source:
BioGRID (unspecified method)

		MIR451A	AIMP1
Description		microRNA 451a	aminoacyl tRNA synthetase complex interacting multifunctional protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Extracellular Exosome Extracellular Vesicle	Extracellular Space Nucleus Endoplasmic Reticulum Golgi Apparatus Cytosol Cell Surface Membrane Aminoacyl-tRNA Synthetase Multienzyme Complex
	Molecular Function		TRNA Binding Cytokine Activity Protein Binding Protein Homodimerization Activity GTPase Binding
	Biological Process	Negative Regulation Of Gene Expression Negative Regulation Of Cell Migration Gene Silencing By MiRNA Positive Regulation Of Vascular Wound Healing Positive Regulation Of Apoptotic Process Negative Regulation Of Protein Kinase B Signaling Positive Regulation Of Vascular Associated Smooth Muscle Cell Migration Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Angiogenesis Negative Regulation Of Endothelial Cell Proliferation TRNA Aminoacylation For Protein Translation Apoptotic Process Inflammatory Response Signal Transduction Cell-cell Signaling Leukocyte Migration Defense Response To Virus Positive Regulation Of Glucagon Secretion
Pathways			Selenoamino acid metabolism Cytosolic tRNA aminoacylation
Drugs
Diseases			Hypomyelinating leukodystrophy (HLD); Pelizaeus-Merzbacher disease (PMD)
GWAS		Mean corpuscular hemoglobin concentration ( 29403010)
Interacting Genes		76 interacting genes: AIMP1 AIMP2 APOBEC3B AQR C1QBP DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EIF2AK2 EPRS1 ERAL1 FUS GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LRPPRC MARS1 MATR3 MSI2 NOL6 NONO NUDT16L1 NUDT21 PDCD11 PGAM5 PRMT1 PTBP1 PTBP3 PUF60 RARS1 RBFOX2 RBM14 RBM4 RTCA RTCB SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SUGP2 SYNCRIP TAF15 TENT2 TRA2A TRA2B UPF1 UTP20 YBX1 YBX2 YBX3 ZNF346	50 interacting genes: AIMP2 APP ATP5F1A HOMER1 IQGAP1 MAPK14 MAPK8 MIR106B MIR107 MIR122 MIR128-1 MIR128-2 MIR138-2 MIR140 MIR15A MIR15B MIR17 MIR199A1 MIR199A2 MIR19B1 MIR19B2 MIR205 MIR206 MIR20B MIR214 MIR222 MIR25 MIR29C MIR31 MIR34A MIR34B MIR34C MIR451A MIR7-1 MIR7-2 MIR7-3 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7I OPTN RARS1 SUMO2 TSNAX
Entrez ID		574411	9255
HPRD ID			04676
Ensembl ID		ENSG00000284565	ENSG00000164022
Uniprot IDs			B4DNK3 Q12904
PDB IDs			1E7Z 1EUJ 1FL0 4R3Z
Enriched GO Terms of Interacting Partners?
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