MIR18B and CELF1

Data Source:
BioGRID (unspecified method)

		MIR18B	CELF1
Description		microRNA 18b	CUGBP Elav-like family member 1
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Cytoplasm Cytoplasmic Stress Granule Membrane Perinucleolar Compartment Ribonucleoprotein Complex
	Molecular Function	MRNA Binding Involved In Posttranscriptional Gene Silencing	Translation Repressor Activity, MRNA Regulatory Element Binding RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding Pre-mRNA Binding BRE Binding
	Biological Process	Negative Regulation Of Epithelial Cell Differentiation Gene Silencing By MiRNA	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splice Site Selection MRNA Processing Germ Cell Development Negative Regulation Of Cell Population Proliferation Embryo Development Ending In Birth Or Egg Hatching Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Cell Death RNA Interference Posttranscriptional Gene Silencing Regulation Of RNA Splicing Regulation Of Inflammatory Response MRNA Destabilization
Pathways
Drugs
Diseases
GWAS			Alcohol use disorder (total score) ( 30336701) Alzheimer's disease ( 31473137) Alzheimer's disease (late onset) ( 24162737) Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Bipolar disorder ( 31043756) Body mass index ( 28552196) Brain morphology (MOSTest) ( 32665545) Estimated glomerular filtration rate ( 30604766) Fruit consumption ( 32066663) Global electrical heterogeneity phenotypes ( 29622589) Glomerular filtration rate ( 29403010) Hand grip strength ( 29691431) Immature fraction of reticulocytes ( 32888494 27863252) Loneliness ( 31518406 29970889) Loneliness (MTAG) ( 29970889) Metabolic syndrome ( 31589552) Neuroticism ( 29255261) Non-lobar intracerebral hemorrhage (MTAG) ( 31430377) Platelet count ( 32888494) Refractive error ( 32231278) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271) Sleep duration (short sleep) ( 30846698) Total cholesterol levels ( 30275531) Type 2 diabetes ( 30297969) Youthful appearance (self-reported) ( 32339537)
Interacting Genes		84 interacting genes: APOBEC3B C1QBP CELF1 CELF2 CPSF1 CPSF6 CPSF7 DARS1 DDX1 DDX21 DDX3X DDX3Y DHX36 EIF2AK2 EPRS1 FAM98A FAM98B FUS GRSF1 HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARP7 LARS1 LIN28A LRPPRC MARS1 MATR3 MSI2 NOL6 NONO NUDT16L1 NUDT21 P3H1 PDCD11 PGAM5 PLOD1 PRMT1 PTBP1 PTBP3 PTCD3 PUF60 PUM1 PURA QARS1 RARS1 RBFOX2 RBM14 RTCB SART3 SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SYNCRIP TAF15 TRA2B TRIM26 TRIM71 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346	46 interacting genes: APP DMPK FUBP1 MIR106B MIR107 MIR10B MIR128-1 MIR138-2 MIR140 MIR143 MIR155 MIR15B MIR17 MIR18B MIR199A1 MIR19A MIR19B1 MIR19B2 MIR205 MIR206 MIR20B MIR21 MIR214 MIR221 MIR25 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR363 MIR7-1 MIR7-2 MIR9-1 MIR9-2 MIR92A1 MIR92A2 MIRLET7A3 MIRLET7B MIRLET7E MIRLET7F1 MIRLET7G MIRLET7I PPBP RALY TOM1L1
Entrez ID		574033	10658
HPRD ID			03046
Ensembl ID		ENSG00000283931	ENSG00000149187
Uniprot IDs			G5EA30 Q92879
PDB IDs			2CPZ 2DHS 2RQ4 2RQC 3NMR 3NNA 3NNC 3NNH
Enriched GO Terms of Interacting Partners?
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