RHOJ and PARD6B

Data Source:
BioGRID (two hybrid)

		RHOJ	PARD6B
Description		ras homolog family member J	par-6 family cell polarity regulator beta
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Extracellular Exosome	Nucleus Cytosol Plasma Membrane Bicellular Tight Junction Cell Cortex Apical Plasma Membrane Protein-containing Complex Extracellular Exosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding	Protein Kinase C Binding Protein Binding
	Biological Process	Angiogenesis Endocytosis Regulation Of Cell Shape Regulation Of Endothelial Cell Migration Cell Migration Cell Projection Assembly Actin Cytoskeleton Organization Cdc42 Protein Signal Transduction Regulation Of Small GTPase Mediated Signal Transduction Retina Vasculature Morphogenesis In Camera-type Eye Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis Regulation Of Sprouting Angiogenesis	Cell-cell Junction Assembly Centrosome Cycle Establishment Or Maintenance Of Cell Polarity Axonogenesis Regulation Of Cell Migration Cell Division Regulation Of Cellular Localization Protein-containing Complex Assembly Bicellular Tight Junction Assembly
Pathways		Rho GTPase cycle	Tight junction interactions
Drugs
Diseases
GWAS		Endometriosis ( 28881265) Heel bone mineral density ( 30598549) Metabolite levels ( 23823483)	Bipolar disorder ( 21771265)
Interacting Genes		25 interacting genes: ACVR1 ADAMTSL4 BHLHE40 BLZF1 BMPR1B CDC42 CDC42EP1 DOCK10 DOCK8 GOLGA2 MEOX2 PAK1 PAK2 PAK3 PAK5 PAK6 PARD6B SMAD2 SMAD4 SSX3 TGFBR1 TRIP10 WAS WASL ZNF426	33 interacting genes: APP ARAP3 BANP CDC42 CDCA4 CEP76 FRMD6 GMCL1 GOLGA2 HSF2BP HTRA1 MAGOHB PALS1 PARD3 PARD3B PARD6A PNMA1 PRKCG PRKCI PRKCZ RAC1 RASSF3 RHOJ RHOQ SIAH1 TCP10L3 TRIB3 TRIM35 WDR83 YWHAB YWHAH YWHAZ ZSCAN4
Entrez ID		57381	84612
HPRD ID		09632	18703
Ensembl ID		ENSG00000126785	ENSG00000124171
Uniprot IDs		A0A024R692 Q7Z513 Q9H4E5	Q9BYG5
PDB IDs
Enriched GO Terms of Interacting Partners?
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