ADAMTSL3 and EFL1

Data Source:
HPRD (in vitro)

		ADAMTSL3	EFL1
Description		ADAMTS like 3	elongation factor like GTPase 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Matrix Intracellular Membrane-bounded Organelle	Cytosol Ribonucleoprotein Complex
	Molecular Function	Metalloendopeptidase Activity Protein Binding	Translation Elongation Factor Activity GTPase Activity GTP Binding Ribosome Binding
	Biological Process	Proteolysis Extracellular Matrix Organization	Translational Elongation Mature Ribosome Assembly GTP Metabolic Process
Pathways		Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins
Drugs			S-(Methylmercury)-L-Cysteine Deoxycholic acid Guanosine-5'-Diphosphate
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Appendicular lean mass ( 28724990) Asthma ( 32296059) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder lithium response (categorical) or schizophrenia ( 29121268) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body size at age 10 ( 32376654) Childhood body mass index ( 33045005) Chronic obstructive pulmonary disease ( 30804561) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Height ( 21998595 28552196 20881960 25282103 25429064 19343178 23563607 31562340 18391950 18391951 18391952 20397748 20189936) Hip circumference ( 25673412) Hip circumference adjusted for BMI ( 28552196 25673412) Lean body mass ( 28724990) Optic disc size ( 31809533) Pulse pressure ( 30224653) Schizophrenia ( 28991256 25056061 29483656 30285260) Spine bone size ( 31053729) Waist circumference ( 26785701) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 28552196 26785701 25673412 28448500)
Interacting Genes		14 interacting genes: CYSRT1 GLRX3 KRT40 KRTAP1-1 KRTAP10-3 KRTAP10-6 KRTAP10-8 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP3-2 KRTAP5-7 MDFI NOTCH2NLA	2 interacting genes: LINC00839 SBDS
Entrez ID		57188	79631
HPRD ID		12426	07812
Ensembl ID		ENSG00000156218	ENSG00000140598
Uniprot IDs		P82987	Q7Z2Z2
PDB IDs			5ANB 5ANC
Enriched GO Terms of Interacting Partners?
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