VARS2 and ABI3

Data Source:
BioGRID (two hybrid)

		VARS2	ABI3
Description		valyl-tRNA synthetase 2, mitochondrial	ABI family member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Cytosol	Intracellular Anatomical Structure Cytoplasm Membrane Lamellipodium
	Molecular Function	Aminoacyl-tRNA Editing Activity Valine-tRNA Ligase Activity Protein Binding ATP Binding	Protein Binding SH3 Domain Binding Identical Protein Binding
	Biological Process	Valyl-tRNA Aminoacylation Aminoacyl-tRNA Metabolism Involved In Translational Fidelity	Peptidyl-tyrosine Phosphorylation Regulation Of Cell Migration
Pathways		Mitochondrial tRNA aminoacylation
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Conotruncal heart defects (maternal effects) ( 28468790) Gestational age at birth (maternal effect) ( 28877031) HIV-1 control ( 20041166) Malaria ( 31844061) Microalbuminuria in type 1 diabetes ( 31537649) Pubertal anthropometrics ( 23449627) Refractive error ( 32231278) Squamous cell lung carcinoma ( 28604730) Ulcerative colitis ( 20848476) Urate levels ( 31578528)	Alzheimer's disease (late onset) ( 28714976) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Asthma ( 31619474) Family history of Alzheimer's disease ( 30617256) Prostate cancer ( 23535732) Refractive error ( 32231278)
Interacting Genes		8 interacting genes: ABI1 ABI2 ABI3 CMTM5 MAL2 NCK2 PIK3CA SORBS3	77 interacting genes: ABI2 ABI3BP ACTN3 AGTR1 ARHGAP9 ARMC7 BAIAP2L2 BFSP2 BLOC1S5 CENPQ CEP170P1 CEP44 CYFIP2 DESI1 DTNB DTNBP1 EIF3H EIF3M EMILIN1 ENAH EVL FAM124B FARSA FBF1 GNG13 GOLM1 GRB2 HOMER1 HOMER2 HOMER3 IFT20 IHO1 KANK2 KIAA0408 KIFC3 KLC3 KLC4 KRT13 KRT14 KRT15 KRT24 KRT28 KRT31 KRT35 KRT36 KRT38 MAGEA12 MED29 MIS18A MRFAP1 MRFAP1L1 NCK2 NDEL1 NHSL2 NUP58 OIP5 PAK1 PAK2 PSMA1 RUFY3 RUNX1T1 SH3BP1 SMARCD1 SNAP23 SOS1 STX1A STX2 SUFU TMEM147 TRAF4 TXN2 VARS2 VASP WAS WASF1 WASF2 WASHC1
Entrez ID		57176	51225
HPRD ID		11670	05900
Ensembl ID		ENSG00000137411	ENSG00000108798
Uniprot IDs		A0A1U9X9B3 B4DG77 B4E0K6 Q5ST30	Q9P2A4
PDB IDs
Enriched GO Terms of Interacting Partners?
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