CAMK1G and CDC45

Data Source:
BioGRID (two hybrid)

		CAMK1G	CDC45
Description		calcium/calmodulin dependent protein kinase IG	cell division cycle 45
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GO Annotations	Cellular Component	Golgi Membrane Intracellular Anatomical Structure Plasma Membrane Calcium- And Calmodulin-dependent Protein Kinase Complex Neuron Projection	Nucleus Nucleoplasm Cytoplasm Centrosome DNA Replication Preinitiation Complex Ciliary Basal Body
	Molecular Function	Calmodulin-dependent Protein Kinase Activity Protein Binding Calmodulin Binding ATP Binding	Chromatin Binding DNA Replication Origin Binding Single-stranded DNA Binding Protein Binding
	Biological Process	Peptidyl-serine Phosphorylation	DNA Replication Checkpoint G1/S Transition Of Mitotic Cell Cycle Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Double-strand Break Repair Via Break-induced Replication DNA Replication DNA Replication Initiation Regulation Of Chromatin Silencing At Telomere Mitotic DNA Replication Preinitiation Complex Assembly
Pathways			Activation of ATR in response to replication stress Unwinding of DNA Activation of the pre-replicative complex G1/S-Specific Transcription
Drugs		SU-11652 Fostamatinib
Diseases
GWAS		Adult body size ( 32376654) Age-related cognitive decline (visuospatial skill) (slope of z-scores) ( 30954325) Amyotrophic lateral sclerosis ( 23624525) Obesity (extreme) ( 21935397)	Cognitive decline rate in late mild cognitive impairment ( 26252872)
Interacting Genes		4 interacting genes: CDC45 KRTAP10-1 KRTAP10-8 PJA1	25 interacting genes: CAMK1G CDK4 CDKN1A CDKN2A CEP55 CSK GINS4 LCK MAPK3 MCM10 MCM2 MCM3 MCM6 MCM7 ORC1 ORC2 ORC3 ORC5 ORC6 POLA1 RAB4B TOPBP1 TRAPPC3 UBC ZRANB1
Entrez ID		57172	8318
HPRD ID		10807	09145
Ensembl ID		ENSG00000008118	ENSG00000093009
Uniprot IDs		Q96NX5	O75419
PDB IDs		2JAM	5DGO 6XTX 6XTY
Enriched GO Terms of Interacting Partners?
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