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PELI1 and CLEC17A
Data Source:
BioGRID
(two hybrid)
PELI1
CLEC17A
Description
pellino E3 ubiquitin protein ligase 1
C-type lectin domain containing 17A
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Condensed Nuclear Chromosome Kinetochore
Cytosol
Cell Surface
Integral Component Of Membrane
Molecular Function
Protein Binding
Ubiquitin-ubiquitin Ligase Activity
Ubiquitin Protein Ligase Activity
Protein Binding
Mannose Binding
Identical Protein Binding
Fucose Binding
Metal Ion Binding
Biological Process
Protein Polyubiquitination
Positive Regulation Of Cytokine Production
Toll Signaling Pathway
Regulation Of Toll Signaling Pathway
Positive Regulation Of B Cell Proliferation
Positive Regulation Of Protein Ubiquitination
Negative Regulation Of NF-kappaB Transcription Factor Activity
Response To Lipopolysaccharide
Positive Regulation Of Toll-like Receptor 3 Signaling Pathway
Positive Regulation Of Toll-like Receptor 4 Signaling Pathway
Negative Regulation Of T Cell Proliferation
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Response To DsRNA
Negative Regulation Of Necroptotic Process
Interleukin-1-mediated Signaling Pathway
Protein K63-linked Ubiquitination
Protein K48-linked Ubiquitination
Pathways
Regulation of necroptotic cell death
Interleukin-1 signaling
IRAK1 recruits IKK complex
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation
Drugs
Diseases
GWAS
Allergic dermatitis (nickel) (
23921680
)
HOMA-B (corrected for HOMA-IR) (
30369944
)
Kawasaki disease (
21221998
)
Iris color (L* coordinate) (
30895295
)
Response to antidepressants (symptom improvement) (
29160301
)
Interacting Genes
31 interacting genes:
BCL6
BIRC3
BUB1B
CLEC17A
CNTROB
GOSR2
IKBKB
INPP5J
IRAK1
IRAK2
IRAK4
IRS1
LCN2
LMNA
MDM4
RIMS4
RIPK1
RIPK3
SRPK1
SRPK2
TP53
TP63
TRIP13
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2I
UBE2N
UBE2V1
VAC14
21 interacting genes:
ASGR2
ATP6V0C
CLDN8
CTXN3
CXCL9
FAM3C
GPR152
IGFBP5
NCK2
NINJ2
OLFM4
PELI1
PELI2
RPRM
SEC23A
SMIM3
TM4SF4
TMEM140
TMEM201
TMEM218
UPK2
Entrez ID
57162
388512
HPRD ID
17834
16993
Ensembl ID
ENSG00000197329
ENSG00000187912
Uniprot IDs
Q53T26
Q96FA3
Q6ZS10
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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