AGTRAP and KCNK5

Data Source:
BioGRID (two hybrid)

		AGTRAP	KCNK5
Description		angiotensin II receptor associated protein	potassium two pore domain channel subfamily K member 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Cell Cortex Integral Component Of Membrane Cytoplasmic Vesicle Membrane Intracellular Membrane-bounded Organelle	Integral Component Of Plasma Membrane
	Molecular Function	Angiotensin Type II Receptor Activity Protein Binding	Voltage-gated Ion Channel Activity Potassium Channel Activity Protein Binding Potassium Ion Leak Channel Activity
	Biological Process	Response To Hypoxia Regulation Of Blood Pressure Angiotensin-activated Signaling Pathway	Potassium Ion Transport Excretion Stabilization Of Membrane Potential Regulation Of Ion Transmembrane Transport Regulation Of Resting Membrane Potential Potassium Ion Transmembrane Transport Potassium Ion Export Across Plasma Membrane
Pathways		Signaling by BRAF and RAF fusions	Phase 4 - resting membrane potential
Drugs
Diseases
GWAS		Arterial stiffness (brachial-femoral pulse wave velocity) ( 32790701) Basophil percentage of white cells ( 32888494) Systolic blood pressure ( 19430483)	Apolipoprotein A1 levels ( 32203549) Coronary artery disease ( 32469254 29212778 26343387 33020668) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Diastolic blood pressure ( 27841878) Eating disorders ( 23568457) HDL cholesterol levels ( 32203549) Kidney stones ( 31729369) Migraine ( 27322543) Myocardial infarction ( 26343387) Obesity-related traits ( 23251661) Social communication problems ( 24564958) Urinary albumin-to-creatinine ratio ( 31630189 31511532) Urolithiasis ( 30975718)
Interacting Genes		138 interacting genes: ACSF2 AGTR1 AGTR2 ALDH18A1 ANKS6 AP3M1 APOA4 AQP6 ARAF ARFIP2 ARHGAP1 ATP5F1E BCL2L13 BPIFA2 CAPNS1 CCDC70 CD160 CD79A CELA3A CIAO2A COQ8A CPLX1 CPLX4 CRCT1 CYB5R3 CYBC1 DDA1 DDX55 DGCR6 DIABLO DNAJC1 ECPAS ERGIC3 ETFRF1 FAM114A1 FAM209A FARS2 FASTKD3 FATE1 FFAR2 FGA FHIP1B FNDC9 GABARAPL2 GAD1 GAD2 GDNF GPR152 GPX8 GTF2H1 GTF3C1 H4C7 HARS2 HIBADH HMGB1 HSBP1L1 HSCB HSD17B13 HSFX1 HSFX2 HSPA4 IL7R ISCU KCNK5 KIR2DL3 KIR3DL3 LMNA LMO2 LNX1 LRRC4C LRRC59 MCEE MGST3 MIEF1 MIEF2 MMD MRM1 MRPL11 MRRF MTERF3 MUTYH MYG1 NDRG4 NDUFAF3 NFU1 NFYB NKG7 PBX3 PCTP PCYT1A PDHX PIMREG PITPNC1 PNPO POLDIP2 PPIF PRPF18 PTPN9 RAB30 RACK1 RBFA RETREG3 RMDN2 S100B SCAND1 SENP2 SH3GLB1 SLC18A1 SLC7A14 SMG9 SNX1 SPG21 SSX3 SSX5 STAG3L1 STAR STARD4 STMN4 STX1A SUCLA2 SYT16 TBRG4 TCEA2 TCEANC2 TFAM THAP4 TMEM139 TMEM14B TMEM31 TMPPE TPD52L3 TTPA TUBA1B TXN2 UBE2I YARS2 ZFYVE21 ZNF391	29 interacting genes: ADIPOQ AGTRAP APP AQP1 ATP5PF BNIP2 CMTM5 COMT CYB5B FRAT1 GJB2 IGFBP5 LHFPL5 MAN2B2 ORMDL3 SLC66A2 SMCO4 STRIT1 TM4SF4 TMEM128 TMEM14A TMEM176A TMEM218 TMEM54 TMEM60 TNFRSF10C TSPAN33 VAMP3 YIPF6
Entrez ID		57085	8645
HPRD ID		16379	04604
Ensembl ID		ENSG00000177674	ENSG00000164626
Uniprot IDs		Q6RW13	A0A024RD32 A0A0B6VPR3 O95279
PDB IDs
Enriched GO Terms of Interacting Partners?
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