LHX9 and LDB2

Data Source:
HPRD (in vitro)

		LHX9	LDB2
Description		LIM homeobox 9	LIM domain binding 2
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleus Nucleoplasm Transcription Regulator Complex Nucleolus Plasma Membrane Cell Leading Edge
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Activating Transcription Factor Binding Transcription Coregulator Activity Protein Binding Enzyme Binding LIM Domain Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Cell Population Proliferation Male Gonad Development Female Gonad Development Neuron Differentiation Gonad Morphogenesis Negative Regulation Of Transcription, DNA-templated Dorsal Spinal Cord Interneuron Anterior Axon Guidance	Negative Regulation Of Transcription By RNA Polymerase II Hair Follicle Development Nervous System Development Epithelial Structure Maintenance Regulation Of Cell Migration Somatic Stem Cell Population Maintenance Regulation Of Kinase Activity Positive Regulation Of Cellular Component Biogenesis Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Regulation of expression of SLITs and ROBOs
Drugs
Diseases
GWAS		General risk tolerance (MTAG) ( 30643258) Heel bone mineral density ( 30598549)	Change in LVEF in response to paclitaxel and trastuzumab in HER2+ breast cancer ( 28763429) Liver fibrosis (total hepatic collagen content) ( 32953199) Number of sexual partners ( 30643258) QT interval ( 23534349) Rhegmatogenous retinal detachment ( 23585552) Systemic juvenile idiopathic arthritis ( 27927641) Waist circumference ( 28552196)
Interacting Genes		9 interacting genes: CSNK2A1 CWF19L2 IGFN1 KHK LDB1 LDB2 SMAD2 SMURF1 UBTFL1	29 interacting genes: C14orf119 CETN3 DGCR6L EGLN3 EPM2AIP1 EXOC3L1 GGACT HDAC7 ISL1 LHX4 LHX8 LHX9 LMO1 LMO2 LMO3 LMO4 LNX1 NTAQ1 PSMB1 RASIP1 RILP RLIM SDCBP SMARCD1 SSBP2 SSBP3 SSBP4 TSNAX TTC19
Entrez ID		56956	9079
HPRD ID		07299	16022
Ensembl ID		ENSG00000143355	ENSG00000169744
Uniprot IDs		H0YL54 Q9NQ69	B7Z6D0 E9PFI4 G5E9Y7 O43679
PDB IDs		2DMQ
Enriched GO Terms of Interacting Partners?
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