SMCO4 and CLTRN

Data Source:
BioGRID (two hybrid)

		SMCO4	CLTRN
Description		single-pass membrane protein with coiled-coil domains 4	collectrin, amino acid transport regulator
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Integral Component Of Membrane	Cytoplasm Plasma Membrane Integral Component Of Membrane Extracellular Exosome
	Molecular Function	Molecular_function Protein Binding	Protein Binding Protein Homodimerization Activity
	Biological Process	Biological_process	Regulation Of Transmembrane Transporter Activity Positive Regulation Of SNARE Complex Assembly Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Calcium Ion-dependent Exocytosis Positive Regulation Of Amino Acid Transport Positive Regulation Of L-proline Import Across Plasma Membrane
Pathways			Insulin processing
Drugs
Diseases
GWAS		Adult body size ( 32376654) Insulin levels in response to oral glucose tolerance test (30 minutes) ( 29093273)
Interacting Genes		59 interacting genes: AQP6 BNIP3L CD79A CLEC10A CLTRN CPLX4 CREB3L1 CXCR2 EBP ERGIC3 FAM174A FAM209A FAM210B FFAR2 GJA8 GKN1 GPA33 GPR152 GPR42 HHLA2 ICAM3 IL10RA KASH5 KCNK5 KIR3DL1 KRT40 KRTAP10-3 KRTAP10-7 LEPROTL1 LMNA LRRC25 M6PR MGST3 MS4A3 MUC1 PEX12 PLD3 PTGES RETREG3 SCN3B SLC16A2 SLC18A1 SLC35C2 SLC41A3 SLC7A1 SLC7A14 SMIM3 SPINT1 STOM SUSD3 SYNE4 SYNPR TEX29 TFEC TMEM139 TMEM80 TMX2 VSIR WBP1	4 interacting genes: OLFM4 RBM18 SMCO4 UBE2J1
Entrez ID		56935	57393
HPRD ID		17008	06668
Ensembl ID		ENSG00000166002	ENSG00000147003
Uniprot IDs		A0A024R3A3 Q9NRQ5	A0A3B3ITM8 Q9HBJ8
PDB IDs
Enriched GO Terms of Interacting Partners?
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