MAP3K7CL and TAB3

Data Source:
HPRD (two hybrid)

		MAP3K7CL	TAB3
Description		MAP3K7 C-terminal like	TGF-beta activated kinase 1 (MAP3K7) binding protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol	Cytosol Plasma Membrane Endosome Membrane Extracellular Exosome
	Molecular Function	Protein Binding	Protein Binding Ubiquitin Binding Metal Ion Binding
	Biological Process		Activation Of MAPK Activity Stimulatory C-type Lectin Receptor Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway I-kappaB Kinase/NF-kappaB Signaling JNK Cascade Negative Regulation Of Autophagy Fc-epsilon Receptor Signaling Pathway Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of NF-kappaB Transcription Factor Activity Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Interleukin-1-mediated Signaling Pathway
Pathways			NOD1/2 Signaling Pathway FCERI mediated NF-kB activation TAK1 activates NFkB by phosphorylation and activation of IKKs complex activated TAK1 mediates p38 MAPK activation JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 TNFR1-induced NFkappaB signaling pathway CLEC7A (Dectin-1) signaling TICAM1,TRAF6-dependent induction of TAK1 complex Interleukin-1 signaling IRAK2 mediated activation of TAK1 complex TRAF6-mediated induction of TAK1 complex within TLR4 complex Alpha-protein kinase 1 signaling pathway IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778 33020668) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Estimated glomerular filtration rate after 1 year in renal transplantation (recipient effect) ( 30920136) Gamma glutamyl transferase levels ( 29403010) Ventricular ectopy ( 29618737) White blood cell count ( 32888494)
Interacting Genes		9 interacting genes: AK8 CISH DDIT4L GPS2 KRT31 KRT34 REL TAB3 USF1	10 interacting genes: CEP57L1 IKBKG MAP3K7 MAP3K7CL OGT PIN1 PPIL3 TAB1 TRAF2 TRAF6
Entrez ID		56911	257397
HPRD ID		10764	06738
Ensembl ID		ENSG00000156265	ENSG00000157625
Uniprot IDs		B0EVZ6 B0EVZ7 B0EVZ8 B4DFW0 P57077	Q8N5C8
PDB IDs
Enriched GO Terms of Interacting Partners?
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