TMEM167B and LSS

		TMEM167B	LSS
Description		transmembrane protein 167B	lanosterol synthase
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Integral Component Of Membrane	Endoplasmic Reticulum Membrane Lipid Droplet Membrane
	Molecular Function	Molecular_function Protein Binding	Lanosterol Synthase Activity Protein Binding Beta-amyrin Synthase Activity
	Biological Process	Constitutive Secretory Pathway	Steroid Biosynthetic Process Cholesterol Biosynthetic Process Triterpenoid Biosynthetic Process Regulation Of Protein Stability Regulation Of Cholesterol Biosynthetic Process
Pathways			Cholesterol biosynthesis Activation of gene expression by SREBF (SREBP)
Drugs			R048-8071 Lanosterol
Diseases
GWAS		Apolipoprotein B levels ( 32203549)	White blood cell count ( 27863252)
Interacting Genes		33 interacting genes: ACKR2 AGPAT3 APOL3 AQP10 AQP6 ASPH C14orf180 CD300C CD47 CTXN3 EBP FXYD6-FXYD2 HSD17B11 HSD17B13 LETMD1 LSS MFSD14B MGST2 PLLP REEP4 SACM1L SEC22B SERINC2 SLC34A3 SMPD2 STX12 STX1B TAS2R19 TM4SF19 TMEM100 TMEM107 UNC50 ZDHHC21	9 interacting genes: AQP6 CIB1 GPR35 NR4A1 SLC10A1 SLC10A6 TMEM167B TMEM86B YIF1A
Entrez ID		56900	4047
HPRD ID		16474	02945
Ensembl ID		ENSG00000215717	ENSG00000160285
Uniprot IDs		A0A024R096 A0A494C0V7 Q9NRX6	B2R694 P48449
PDB IDs			1W6J 1W6K
Enriched GO Terms of Interacting Partners?
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