CELF4 and DSC2

Data Source:
HPRD (in vitro)

		CELF4	DSC2
Description		CUGBP Elav-like family member 4	desmocollin 2
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Ribonucleoprotein Complex	Cornified Envelope Plasma Membrane Cell-cell Junction Adherens Junction Intercalated Disc Integral Component Of Membrane Desmosome Cytoplasmic Vesicle Extracellular Exosome
	Molecular Function	Translation Repressor Activity, MRNA Regulatory Element Binding RNA Binding MRNA Binding Pre-mRNA Binding BRE Binding	Calcium Ion Binding Protein Binding Cell Adhesive Protein Binding Involved In Bundle Of His Cell-Purkinje Myocyte Communication
	Biological Process	Alternative MRNA Splicing, Via Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome In Utero Embryonic Development MRNA Splice Site Selection Germ Cell Development Embryo Development Ending In Birth Or Egg Hatching Negative Regulation Of Translation Negative Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Excitatory Postsynaptic Potential Regulation Of Retina Development In Camera-type Eye	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Cellular Response To Starvation Keratinization Cornification Cardiac Muscle Cell-cardiac Muscle Cell Adhesion Bundle Of His Cell-Purkinje Myocyte Adhesion Involved In Cell Communication Regulation Of Heart Rate By Cardiac Conduction Cell-cell Adhesion Regulation Of Ventricular Cardiac Muscle Cell Action Potential
Pathways			Keratinization Formation of the cornified envelope
Drugs
Diseases			Arrhythmogenic right ventricular cardiomyopathy (ARVC)
GWAS		Body fat mass ( 28552196) Chronotype ( 30696823) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Educational attainment ( 25201988) Experiencing mood swings ( 29500382) Feeling fed-up ( 29500382) Feeling guilty ( 29500382) Feeling hurt ( 29500382) Feeling miserable ( 29500382) General factor of neuroticism ( 30867560) Household income ( 31844048) Household income (MTAG) ( 31844048) Mood instability ( 31168069) Neurociticism ( 29500382) Neuroticism ( 27089181 27067015) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245) Refractive error ( 32231278) Worry too long after an embarrassing experience ( 29500382)	Blood protein levels ( 30072576 29875488) Bronchopulmonary dysplasia ( 23897914) Metabolite levels ( 23823483)
Interacting Genes		10 interacting genes: APP LYST PCBP3 PRR20A PRR20B PRR20C PRR20D PRR20E RBPMS2 TIAL1	6 interacting genes: CLK1 DSG1 DSG2 JUP PKP2 PKP3
Entrez ID		56853	1824
HPRD ID		12534	00512
Ensembl ID		ENSG00000101489	ENSG00000134755
Uniprot IDs		Q9BZC1	A0A3B3ISU0 Q02487
PDB IDs		2DGP 2DNK	5ERP 5J5J
Enriched GO Terms of Interacting Partners?
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